108546-81-2Relevant academic research and scientific papers
1-Amino-1-hydroxymethylcyclobutane derivatives via intramolecular amination of nonclassical cyclopropylmethyl cation
Skvorcova, Marija,Grigorjeva, Liene,Jirgensons, Aigars
, (2017)
[Figure not available: see fulltext.] Bis(trichloroacetimidoyloxymethyl)cyclopropanes provide intramolecular amination products of intermediate cyclobutyl or cyclopropylmethyl carbenium ion when exposed to Lewis acid catalyst or thermal ionization. The ra
PROCESS FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE DERIVATIVE AND OPTICAL RESOLVER THEREFOR
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, (2008/06/13)
The present invention provides a method of producing an optically active form of a compound represented by the formula (I) having a steroid C17,20-lyase inhibitory activity and is useful as an agent for the prophylaxis or treatment of prostatis
Generation and Reactions of Lithiated tert-Butyl and 2,6-Di(tert-butyl)-4-methylphenyl Cyclopropanecarboxylates
Haener, Robert,Maetzke, Thomas,Seebach, Dieter
, p. 1655 - 1665 (2007/10/02)
tert-Butyl and 2,6-di(tert-butyl)-4-methylphenyl (BHT) cyclopropanecarboxylates (4, 6, 24, 25) are lithiated with LiN(i-Pr)2 and t-BuLi, respectively.Reactions with alkyl halides, aldehydes, acyl chlorides, and heteroelectrophiles give α-substituted BHT esters which can be cleaved (t-BuOK/H2O/THF) to the corresponding carboxylic acids or reduced (LiAlH4/THF) to the cyclopropanemethanols.
