108664-23-9 Usage
Molecular weight
249.26 g/mol
Type of compound
Synthetic chemical compound
Pharmaceutical applications
Potential use in medicinal chemistry
Structural components
a. Pyridin-2(1H)-one ring
b. Benzoylvinyl group attached to the pyridin-2(1H)-one ring
Role in organic synthesis
Valuable building block for the synthesis of various organic compounds
Significance for researchers
Unique structure and chemical properties make it a valuable tool for researchers and medicinal chemists working on the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 108664-23-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,6,6 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 108664-23:
(8*1)+(7*0)+(6*8)+(5*6)+(4*6)+(3*4)+(2*2)+(1*3)=129
129 % 10 = 9
So 108664-23-9 is a valid CAS Registry Number.
108664-23-9Relevant articles and documents
Synthesis and Antifungal Activity of a Series of Novel 1,2-Disubstituted Propenones
Ogata, Masaru,Matsumoto, Hiroshi,Kida, Shiro,Shimizu, Sumio,Tawara, Katsuya,Kawamura, Yoshimi
, p. 1497 - 1502 (2007/10/02)
To find an antifungal agent other than those of the imidazole and triazole series, a new class of 1,2-disubstituted propenones I and II was prepared and tested for antifungal activity.Comparison of the structure-activity relationships showed that the conjugated structure of carbonyl and exomethylene groups in I and II plays an important role in potent antifungal acivity.However, it is noteworthy that compounds 53, 54, and 56, which have a hydroxymethyl or methoxymethyl group instead of an exo-methylene group in I, also showed potent activity.Although many compounds exhibited strong antifungal activity in vitro, none showed activity in vivo of oral efficacy against subacute systemic candidiasis in mice. '