108791-03-3

Upstream product

• 1733-57-9 ethydiphenylphosphine oxide 
• 286-20-4 cyclohexane-1,2-epoxide 
• 144863-57-0 -2-(1-Diphenylphosphinoylethyl)cyclohexanol 
• 144863-57-0 -2-(1-Diphenylphosphinoylethyl)cyclohexanol 
• 108791-03-3 -2-(1-Diphenylphosphinoylethyl)cyclohexanone 

Downstream Products

• 108791-03-3 -2-(1-Diphenylphosphinoylethyl)cyclohexanone 
• 97509-80-3 -7-(1-Diphenylphosphinoylethyl)-oxepan-2-one 
• 108791-04-4 (R)-3-[(R)-1-(Diphenyl-phosphinoyl)-ethyl]-oxepan-2-one 
• 97509-80-3 -7-(1-Diphenylphosphinoylethyl)-oxepan-2-one 
• 108791-04-4 -3-(1-Diphenylphosphinoylethyl)-oxepan-2-one 
• 18357-17-0 diphenylphosphinate anion 

Relevant academic research and scientific papers

Stereochemically Controlled Synthesis of Unsaturated Acids by the Coupled Baeyer-Villiger and Horner-Wittig Reactions: Synthesis of (Z)-Oct-6-enoic Acid

The lithium derivative of Ph2P(O)Et reacts with cyclohexene oxide to give largely one diastereoisomer of an alcohol.Oxidation to a ketone and then to a lactone followed by hydrolysis gives a Horner-Wittig intermediate and hence pure (Z)-oct-6-enoic acid.C

THE STEREOCHEMICALLY CONTROLLED HORNER-WITTIG ROUTE TO UNSATURATED ACIDS: THE BAEYER-VILLIGER REARRANGEMENT OF α-(1-Ph2PO-ALKYL)-CYCLOHEXANONES

Lithiated alkyl diphenylphosphine oxides attack cyclic epoxides with high stereoselectivity: Baeyer-Villiger rearrangement of the derived ketones gives Horner-Wittig intermediates for the synthesis of Z unsaturated acids