1088565-34-7Relevant academic research and scientific papers
Coupling of aldehydes, amines, and trimethyl phosphite promoted by amberlyst-15: Highly efficient synthesis of α-aminophosphonates
Tajbakhsh, Mahmood,Heydari, Akbar,Alinezhad, Heshmatollah,Ghanei, Mercedeh,Khaksar, Samad
, p. 352 - 354 (2008)
A three-component reaction promoted by Amberlyst-15 of an amine, an aldehyde, and trimethyl phosphite (Kabachnik-Fields reaction) in one pot under mild conditions affords the corresponding α-aminophosphonate in high yield after a short reaction time at ambient temperature. Georg Thieme Verlag Stuttgart.
A sulfonic acid functionalized ionic liquid as a homogeneous and recyclable catalyst for the one-pot synthesis of α-aminophosphonates
Akbari, Jafar,Heydari, Akbar
experimental part, p. 4236 - 4238 (2009/10/26)
A sulfonic acid functionalized ionic liquid is used as a Br?nsted acid catalyst for the one-pot, three-component synthesis of α-aminophosphonates from aldehydes and ketones at room temperature in water. This homogeneous catalytic procedure is simple and e
Organocatalytic synthesis of α-hydroxy and α-aminophosphonates
Vahdat, Seyed Mohammad,Baharfar, Robabeh,Tajbakhsh, Mahmood,Heydari, Akbar,Baghbanian, Seyed Meysam,Khaksar, Samad
scheme or table, p. 6501 - 6504 (2009/04/06)
A new and highly flexible procedure is described for the synthesis of α-amino- and α-hydroxy phosphonates. In the presence of a catalytic amount of oxalic acid (10 mol %), trimethyl phosphite reacts with aldehydes or imines (generated in situ from an aldehyde and an amine) to yield the corresponding coupled products in good yield.
