6005-76-1

Upstream product

• 60773-92-4 β-benzalpropionic acid chloride 
• 53106-73-3 (4-phenyl-buta-1,3-dienyl)-carbamic acid methyl ester 
• 770-36-5 4-phenylbuta-3-en-1-ol 
• 98-95-3 nitrobenzene 
• 1515-78-2 buta-1,3-dien-1-ylbenzene 

Downstream Products

• 91-20-3 naphthalene 
• 1088565-34-7 C₁₈H₂₂NO₃P 
• 1088565-52-9 C₁₂H₁₇O₄P 
• 104-54-1 3-Phenylpropenol 
• 725-51-9 2,2-dimethyl-5-(3-phenyl-allyl)-oxazolidin-4-one 
• 714-18-1 2-hydroxy-5-phenyl-pent-4-enoic acid amide 

Relevant academic research and scientific papers

Synthesis of a novel six membered CNS palladacycle; TD-DFT study and catalytic activity towards microwave-assisted selective oxidation of terminal olefin to aldehyde

This article documented synthesis of a Schiff base, E-2-(benzylthio)-N-{(2-methoxynaphthalene-1-yl)methylene}benzenamine (HL) by the treatment of 2-meyhoxynaphthaldehyde and 2-(benzylthio)aniline. Reaction of this synthesized Schiff base with Na2PdCl4has been investigated, which gave a novel six membered Pd(II) complex (PdLCl) through C,N,S-donor atom of Schiff base. These two newly synthesized compounds were characterized by1H NMR, FTIR and UV–Vis spectra and structure of the Pd(II) complex was confirmed by X-ray crystallography. The catalyst (PdLCl) displayed considerable reactivity (up to 99% selectivity and 90% yield) in the selective oxidation of terminal [Formula presented] bond in aryl substituted olefin to aldehyde. The method shows good functional groups compatibility, no ketone byproducts and is operationally simple. Time dependent density functional study (TD-DFT) of representative cyclopalladated complex has been undertaken. The simulated optical spectrum of the complex is in good agreement with the experimentally observed spectrum.

One-pot preparation of imines from nitroarenes by a tandem process with an Ir-Pd heterodimetallic catalyst

A new tandem catalytic process has been studied for a heterodimetallic complex containing both iridium and palladium fragments connected by a 1,2,4-trimethyltriazolyldiylidene ligand. The process implies the unprecedented preparation of imines from the direct reaction of nitroarenes and primary alcohols. The global process comprises the following steps: 1) reduction of the nitroarene to an amine, 2) oxidation of the alcohol to aldehyde, and 3) condensation of the aldehyde and the amine to form the corresponding imine. The oxidation of the alcohol to aldehyde is promoted by the iridium fragment, while the reduction of the nitro group to amine is facilitated by palladium. A wide set of different catalytic systems has been studied, showing that the Ir/Pd complex 1 is a highly active and stable catalyst in the preparation of imines.