1088565-52-9Relevant academic research and scientific papers
Organocatalytic synthesis of α-hydroxy and α-aminophosphonates
Vahdat, Seyed Mohammad,Baharfar, Robabeh,Tajbakhsh, Mahmood,Heydari, Akbar,Baghbanian, Seyed Meysam,Khaksar, Samad
scheme or table, p. 6501 - 6504 (2009/04/06)
A new and highly flexible procedure is described for the synthesis of α-amino- and α-hydroxy phosphonates. In the presence of a catalytic amount of oxalic acid (10 mol %), trimethyl phosphite reacts with aldehydes or imines (generated in situ from an aldehyde and an amine) to yield the corresponding coupled products in good yield.
