1088976-74-2Relevant academic research and scientific papers
Synthesis, characterization, crystal structures and antibacterial activities of some Schiff bases with N2O2 donor sets
Ardakani, Amir Adabi,Kargar, Hadi,Feizi, Nourollah,Tahir, Muhammad Nawaz
, p. 1495 - 1504 (2018)
A series of Schiff base compounds were synthesized by the reaction of different 3,5-dihalosalicylaldehyde (halo atoms equal to Cl, Br and I) with polymethylenediamines of varying chain length. The Schiff bases were characterized using FT-IR, UV–Vis,
Design, synthesis, and pharmacological investigation of iodined salicylimines, new prototypes of antimicrobial drug candidates
Xu, Suo-Ping,Lv, Peng-Cheng,Shi, Lei,Zhu, Hai-Liang
, p. 282 - 290 (2011/07/08)
A series of 3,5-diiodo-salicylalidene Schiff bases (compounds 1 - 35) has been synthesized and tested for antimicrobial activity. The compounds were assayed for antibacterial activities by the MTT method. Some of the compounds inhibit the growth of a broad range of bacteria including the species of Bacillus subtilis, Staphylococcus aureus, Streptococcus faecalis, Pseudomonas aeruginosa, Escherichia coli, and Enterobacter cloacae. Among them, compounds 2-[(4-chloro-phenylimino)-methyl]-4,6-diiodo-phenol 11 and 2,4-diiodo-6-[(2- morpholin-4-yl-ethylimino)methyl]phenol 19 showed the most potent antibacterial activity with MIC of 3.1, 12.9, 3.3, 6.5, 12.9, 3.3 and 3.2, 12.8, 3.2, 12.8, 12.8, 3.2 μM against B. subtilis, S. aureus, S. faecalis, P. aeruginosa, E. Coli, and E. cloacae, respectively.
