108925-71-9

Upstream product

• 91-56-5 indole-2,3-dione 
• 79-37-8 oxalyl dichloride 
• 69314-18-7 N,N'-oxalyl-bis-isatin 
• 124-40-3 dimethyl amine 

Relevant academic research and scientific papers

Studies of the reaction between indole-2,3-diones (isatins) and secondary aliphatic amines

Simple secondary aliphatic amines react with isatin to yield, depending on the structure, either 2-amino-phenylglyoxamides, such as 2-amino-N,N-dimethylphenylglyoxamide, or dialkylammonium salts of 2-aminophenylglyoxylic acids. Reaction of isatin with N,N′-dimethylethylenediamine gave an unusual 2:1 product, whose structure has been determined by X-ray crystallography. Acta Chemica Scandinavica 1997.

Metal Template Reactions. XXIII. Synthesis of Macrocyclic Amide and Ester complexes via 1,1'-Oxalylbisisatin

1,1'-Oxalylbisisatin (7) has been prepared and converted readily into a wide range of glyoxylic esters and amides (10) from which the macrocyclic metal complexes (11)-(16) have been obtained.