1089280-53-4

Basic information

• Product Name: tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate
• Synonyms: tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-(4-amino-3-methoxyphenyl)-, 1,1-dimethylethyl ester
• CAS NO: 1089280-53-4
• Molecular Formula: C₁₇H₂₆N₂O₃
• Molecular Weight: 306.39994
• EINECS: -0
• Mol File: 1089280-53-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 435.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.113±0.06 g/cm3(Predicted)
• PKA: 4.90±0.10(Predicted)
• CAS DataBase Reference: tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate(1089280-53-4)
• EPA Substance Registry System: tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate(1089280-53-4)

Safety Data

• Hazardous Substances Data: 1089280-53-4(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate is a chemical compound with a molecular structure consisting of a piperidine ring substituted with a tert-butyl ester group and a 4-(4-amino-3-methoxyphenyl) moiety. It is commonly used in chemical and pharmaceutical research as a building block or intermediate in the synthesis of various organic compounds. Its specific characteristics and properties make it useful in the development of potential drug candidates and in the study of structure-activity relationships for various biological targets. Additionally, its versatile structure allows for further modification and derivatization to explore potential biological activities and interactions. Overall, tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate has important applications in medicinal chemistry and organic synthesis.

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Downstream Products

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• 1315513-76-8 7-Amino-2-[4-(1-cyclopropylpiperid-4-yl)-2-methoxyphenylamino]-8-(2-hydroxy-2-methylpropyl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 
• 1315513-52-0 7-amino-2-{4-[1-(2-chloroethyl)piperid-4-yl]-2-methoxyphenylamino}-8-(2-hydroxy-2-methylpropyl)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide 

Relevant articles and documents

HETEROCYCLIC COMPOUND

The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.

Tyrosine Kinase Inhibitor And Uses Thereof

Disclosed is a compound of Formula (I) or a pharmaceutically acceptable salt, ester, or solvate thereof, or their stereoisomers, which can be used as tyrosine kinase inhibitor. Also disclosed is a method for preparing the compound, a pharmaceutical composition and a kit comprising the compound, and uses of the compound. The compound can be used as tyrosine kinase inhibitor, or can be used to reduce or inhibit activity of EGFR or mutant thereof, such as EGFR mutant comprising T790M mutation, in a cell, or to treat and/or prevent a disease associated with overactivity of EGFR, such as cancer.

5 OXO-5,8-DIHYDROPYRIDO[2,3-d]PYRIMIDINE DERIVATIVES AS CAMKII KINASE INHIBITORS FOR TREATING CARDIOVASCULAR DISEASES

The present invention relates to 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine derivatives, to their preparation and to their therapeutic use.