1089282-34-7

Upstream product

• 1089282-33-6 1-(2-fluoroethyl)-4-(3-methoxy-4-nitrophenyl)-1,2,3,6-tetrahydropyridine 
• 1124330-12-6 tert-butyl (2-methoxy-4-(piperidin-4-yl)phenyl)aminocarboxylate 
• 59557-91-4 4-bromo-2-methoxyaniline 
• 262433-01-2 (4-bromo-2-methoxyphenyl)carbamic acid tert-butyl ester 
• 1116228-85-3 4-(3-methoxy-4-nitro-phenyl)-1,2,3,6-tetrahydropyridine 
• 1233145-65-7 4-(3-methoxy-4-nitro-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 6627-53-8 1-chloro-3-methoxy-4-nitrobenzene 

Relevant academic research and scientific papers

Tyrosine Kinase Inhibitor And Uses Thereof

Disclosed is a compound of Formula (I) or a pharmaceutically acceptable salt, ester, or solvate thereof, or their stereoisomers, which can be used as tyrosine kinase inhibitor. Also disclosed is a method for preparing the compound, a pharmaceutical composition and a kit comprising the compound, and uses of the compound. The compound can be used as tyrosine kinase inhibitor, or can be used to reduce or inhibit activity of EGFR or mutant thereof, such as EGFR mutant comprising T790M mutation, in a cell, or to treat and/or prevent a disease associated with overactivity of EGFR, such as cancer.