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Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI) is a chemical compound with the molecular formula C13H18BrNO3. It is an ester of carbamic acid and is typically used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals. This colorless to pale yellow liquid has a molecular weight of 303.192 g/mol and should be handled with caution due to potential health risks if ingested, inhaled, or in contact with skin and eyes.

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  • Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI)

    Cas No: 262433-01-2

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  • 262433-01-2 Structure
  • Basic information

    1. Product Name: Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI)
    2. Synonyms: Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI);tert-butyl (4-bromo-2-methoxyphenyl)carbamate
    3. CAS NO:262433-01-2
    4. Molecular Formula: C12H16BrNO3
    5. Molecular Weight: 302.16434
    6. EINECS: N/A
    7. Product Categories: N-BOC
    8. Mol File: 262433-01-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 313.5°Cat760mmHg
    3. Flash Point: 143.4°C
    4. Appearance: /
    5. Density: 1.382g/cm3
    6. Vapor Pressure: 0.000496mmHg at 25°C
    7. Refractive Index: 1.558
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
    11. NIST Chemistry Reference: Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI)(262433-01-2)
    12. EPA Substance Registry System: Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI)(262433-01-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 262433-01-2(Hazardous Substances Data)

262433-01-2 Usage

Uses

Used in Pharmaceutical Industry:
Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI) is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, Carbamic acid, (4-bromo-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI) is utilized as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its role in these applications is crucial for the development of effective and targeted agricultural products that can protect crops and enhance agricultural productivity.

Check Digit Verification of cas no

The CAS Registry Mumber 262433-01-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,2,4,3 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 262433-01:
(8*2)+(7*6)+(6*2)+(5*4)+(4*3)+(3*3)+(2*0)+(1*1)=112
112 % 10 = 2
So 262433-01-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H16BrNO3/c1-12(2,3)17-11(15)14-9-6-5-8(13)7-10(9)16-4/h5-7H,1-4H3,(H,14,15)

262433-01-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-(4-bromo-2-methoxyphenyl)carbamate

1.2 Other means of identification

Product number -
Other names 4-Bromo-2-methoxy-N-Boc-aniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:262433-01-2 SDS

262433-01-2Relevant articles and documents

Tyrosine Kinase Inhibitor And Uses Thereof

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Paragraph 0678-0679, (2017/05/15)

Disclosed is a compound of Formula (I) or a pharmaceutically acceptable salt, ester, or solvate thereof, or their stereoisomers, which can be used as tyrosine kinase inhibitor. Also disclosed is a method for preparing the compound, a pharmaceutical composition and a kit comprising the compound, and uses of the compound. The compound can be used as tyrosine kinase inhibitor, or can be used to reduce or inhibit activity of EGFR or mutant thereof, such as EGFR mutant comprising T790M mutation, in a cell, or to treat and/or prevent a disease associated with overactivity of EGFR, such as cancer.

Polymerizable liquid crystal compound

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Paragraph 0117; 0118, (2019/04/02)

PROBLEM TO BE SOLVED: To provide a polymerizable compound giving high refractive index anisotropy, a wide liquid crystal phase temperature range and high storage stability to a liquid crystal composition and producing a polymer film having high pattern resolution, high heat resistance, and little haze and white irregularity when polymerizing the liquid crystal composition. SOLUTION: The polymerizable compound is represented by general formula (I). The polymerizable liquid crystal composition contains the polymerizable compound as a structural member. COPYRIGHT: (C)2013,JPOandINPIT

Thienopyridine kinase inhibitors

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Page 40, (2008/06/13)

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Thienopyridine and furopyridine kinase inhibitors

-

, (2008/06/13)

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Thienopyridine and furopyridine kinase inhibitors

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Page/Page column 49, (2010/02/10)

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Aryl carbamate derivatives, preperation and use thereof

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Page/Page column 5, (2010/02/06)

The present invention relates to novel compounds, the preparation and use, particularly therapeutic, thereof. More specifically, it relates to compounds derived from aryl carbamates, the preparation and use thereof, particularly in the field of human and animal health. The compounds according to the invention are preferably 5-HT4 serotoninergic receptor ligands and can therefore be used in the therapeutic or prophylactic treatment of any disorder involving a 5-HT4 receptor. The invention also relates to pharmaceutical compositions comprising such compounds, the preparation and use thereof and treatment methods using said compounds.

Solid-phase synthesis of 2-methoxyaniline derivatives by the traceless silicon linker strategy

Curtet, Sophie,Langlois, Michel

, p. 8563 - 8566 (2007/10/03)

Application of the silicon linkage strategy to the solid-phase synthesis of the rich-electron o-anisidine derivatives is described. The protective t-Boc group was easily removed with B-catechol borane and the isocyanate was successfully prepared with the mild reagent (t-Boc)2O/DMAP. Carbamates, ureas or amides were prepared and released by cleavage with TFA at room temperature. This method can be used to prepare small focused libraries with biological activity at serotonin receptors.

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