108945-28-4

Upstream product

• 2216-51-5 (-)-menthol 
• 79-10-7 acrylic acid 
• 89-78-1 menthol 
• 814-68-6 acryloyl chloride 
• 15356-70-4 menthol 
• 86198-29-0 cyclohexanone oxime acrylate 
• 15356-60-2 (1S,2R,5S)-(+)-menthol 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 1315276-27-7 C₂₇H₃₂N₂O₃ 
• 1315276-12-0 C₂₁H₂₇NO₄ 
• 132455-34-6 (2S,4S,5R)-2-Methyl-5-phenyl-pyrrolidine-2,4-dicarboxylic acid 4-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester 2-methyl ester 
• 132455-44-8 (2R,4S,5R)-2,5-Diphenyl-pyrrolidine-2,4-dicarboxylic acid 4-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester 2-methyl ester 
• 132455-33-5 (2S,4S,5R)-5-Naphthalen-2-yl-pyrrolidine-2,4-dicarboxylic acid 4-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester 2-methyl ester 
• 132490-24-5 (2S,3R,5R)-5-Naphthalen-2-yl-pyrrolidine-2,3-dicarboxylic acid 2-isopropyl ester 3-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester 
• 161201-92-9 1S,2R,5S-menthyl-r-2S-methoxycarbonyl-2-methyl-c-5S-(2'-iodophenyl)pyrrolidine-c-4R-carboxylate 
• 161201-94-1 1S,2R,5S-menthyl r-2S-methoxycarbonyl-2-phenyl-c-5S-(2'-iodophenyl)pyrrolidine-c-4R-carboxylate 
• 161201-93-0 1S,2R,5S-menthyl 2S-benzyl-r-2-methoxycarbonyl-c-5S-(2'-iodophenyl)pyrrolidine-c-4R-carboxylate 
• 161201-95-2 1S,2R,5S-menthyl r-2S-methoxycarbonyl-2-methyl-c-5S-(4'-iodo-N-phenylsuphonylindol-3'-yl)pyrrolidine-c-4R-carboxylate 
• 161201-97-4 1S,2R,5S-menthyl r-2S-methoxycarbonyl-2-phenyl-c-5S-(4'-iodo-N-phenylsuphonylindol-3'-yl)pyrrolidine-c-4R-carboxylate 
• 161201-96-3 1S,2R,5S-menthyl 2S-benzyl-r-2-methoxycarbonyl-c-5S-(4'-iodo-N-phenylsuphonylindol-3'-yl)pyrrolidine-c-4R-carboxylate 

Relevant academic research and scientific papers

Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline Hexamers

To produce a novel class of structurally ordered poly-β-prolines, an emergent method for synthesizing chiral β-peptide molecular frameworks was developed based on 1,3-dipolar cycloaddition chemistry of azomethine ylides. Functionalized short β-peptides wi

Chiral activated alkenes induced asymmetric Baylis-Hillman reaction in Me3N/H2O/solvent medium

Chiral-activated alkenes, L-menthyl acrylate and (+)-N-α-phenylethyl acrylamide, induced asymmetric Baylis-Hillman reaction of aromatic aldehydes was realized at 25°C for 7 days in Me3N/H2O/solvent homogeneous medium. The correspondi

A Method For Preparing (Meth)Acrylic Acid Ester Based Compound

The invention relates to a method for preparing a (meth)acrylic acid ester-based compound, and according to the preparation method, a (meth)acrylic acid ester-based compound can be prepared with high purity and high yield, by easily introducing an acrylic structure into alcohol using a diamine-based compound and acid anhydride.

Ru(II)-Catalyzed Oxidative Olefination of Benzamides: Switchable Aza-Michael and Aza-Wacker Reaction for Synthesis of Isoindolinones

Selective tandem oxidative C-H olefination-aza-Michael/aza-Wacker reaction of N-arylbenzamides is achieved by fine-tuning between base and additive to access valuable 3-oxoisoindolinyls and 3-oxoisoindolinylidenes, respectively. Careful optimization and c

Four Stereoisomers of 2-Aminomethyl-1-cyclopropanecarboxylic Acid: Synthesis and biological evaluation

Here, we report a practical method for asymmetric synthesis of cyclopropane-fused GABA analogs. Starting from 2-furaldehyde, the cis-isomer (CAMP) was synthesized over 10 steps; (1)- and (+)-CAMP￠HCl were synthesized by employing d- and l-menth

Photoredox/Cobalt Dual Catalysis for Visible-Light-Mediated Alkene-Alkyne Coupling

Dual photoredox transition-metal catalysis has recently emerged as a powerful tool for making synthetically challenging carbon-carbon bonds under milder reaction conditions. Herein, we report on the visible-light-mediated controlled generation of low-valent cobalt catalyst without the need for a metallic reductant. It enabled C-C bond formation via ene-yne coupling at room temperature. The generality of this dual catalysis is demonstrated via the creation of sizable molecular diversity with the accommodation of several functional groups.

Photoredox-Coupled F-Nucleophilic Addition: Allylation of gem-Difluoroalkenes

A novel strategy for the expedient construction of CF3-embeded tertiary/quarternary carbon centers was developed by taking advantage of photoredox catalysis. Thanks to a key step of single-electron oxidation, electron-rich gem-difluoroalkenes, which otherwise are essentially reluctant towards F-nucleoplilic addition, now readily participate in this fluoroallylation reaction. Furthermore, this strategy provides an elegant example for the generation, as well as functionalization, of α-CF3-substituted benzylic radical intermediates using cheap and readily available starting materials.

Intermolecular Carboamination of Unactivated Alkenes

Herein, we report the first example of group transfer radical addition of O-vinylhydroxylamine derivatives onto unactivated alkenes. By utilizing O-vinylhydroxylamine derivatives as both the N- and C-donors, this reaction enables intermolecular carboamination of unactivated alkenes in an atom economical fashion. As the process is initiated through N-radical addition followed by C-transfer, linear carboamination products are afforded. This differs from canonical radical carbofunctionalization of olefins, which typically favors branched product owing to initiation by C-radical addition.

METALLOPROTEASE INHIBITORS, METHODS FOR PRODUCING SAME, AND THERAPEUTIC USES THEREOF

The invention relates to new α-vinyl carbonylated compounds corresponding to general formula (I), wherein R1, R2, R3, R4, R5 and Y are as defined in claim 1, their isomers, their diastereoisomers and

METHOD OF FABRICATING ACRYLIC MONOMER COMPRISING ALIPHATIC CYCLIC COMPOUND DERIVED NATURAL AND ACRYLIC MONOMER FABRICATED THEREBY AND ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITION INCLUDING THE SAME

Provided are a synthesis method of an acrylic monomer comprising a naturally derived aliphatic cyclic compound, an acrylic monomer synthesized thereby, and an acrylic pressure-sensitive adhesive composition comprising the same. More particularly, the synthesis method comprises the steps of: preparing a naturally derived aliphatic cyclic compound including a hydroxyl functional group at the end; and having a reaction between the aliphatic cyclic compound and an acrylic acid derivative and synthesizing an acrylic monomer comprising a naturally derived aliphatic cyclic compound. Therefore, the acrylic pressure-sensitive adhesive composition has enhanced adhesive strength when bonded to an object by the acrylic monomer synthesized with a naturally derived aliphatic cyclic compound, and can easily separate a panel from an LCD by being capable of easily detached therefrom. Further, the acrylic pressure-sensitive adhesive composition can have minimized environmental burden by being synthesized with a naturally derived aliphatic cyclic compound.(S10) Step of preparing a naturally derived aliphatic cyclic compound including a hydroxyl functional group at the end(S20) Step of having a reaction between the aliphatic cyclic compound and an acrylic acid derivative and synthesizing an acrylic monomer comprising a naturally derived aliphatic cyclic compoundCOPYRIGHT KIPO 2016