108958-54-9Relevant academic research and scientific papers
STUDIES IN SPIROHETEROCYCLES: PART IX : A NEW ELEGANT SYNTHESIS AND REACTIONS OF SOME NOVEL FLUORINE-CONTAINING SPIRO-2,4'(1H)-DIONES
Joshi, Krishna C.,Dandia, Anshu,Ahmed, Nidhal
, p. 2479 - 2485 (2007/10/02)
A number of novel fluorine-containing spiro-2,4'(1H)-diones have been synthetized by an elegant one-step procedure involving the condensation of fluorine-containing indole-2,3-diones, fluorinated aromatic amines and 3-mercaptopropanoic acid without isolating the intermediate isatin-3-anils.The spiro compounds have been further subjected to acetylation, chloroacetylation and Mannich reactions.N-Acetylated spiro compound was simultaneously synthetized from 1-acetylindole-2,3-dione and aniline.The structures of all the compounds have been confirmed on the basic of elemental analyses, ir, 1H nmr, 13C nmr, 19F nmr and mass spectral studies.
