108958-65-2Relevant academic research and scientific papers
ACETALS OF LACTAMS AND ACID AMIDES. 47.* INVESTIGATION OF THE BEHAVIOR OF SUBSTITUTED 6-(β-DIMETHYLAMINO)VINYL-4-PYRIMIDINONES IN ACID MEDIA. SYNTHESIS OF 3-CYANO-4-ANILINO-5-FORMYL-2-PYRIDONE AND 3-CHLORO-4-CYANOBENZONAPHTHYRIDINE
Yalysheva, N.Z.,Solov'eva, N.P.,Chistyakov, V.V.,Sheinker, Yu.N.,Granik, V.G.
, p. 909 - 914 (1986)
The hydrolysis of 1-substituted 5-cyano-6-(β-dimethylamino)vinyl-4-pyrimidinones in acidic media was studied.It was shown that the 1-benzyl derivative is converted to a mixture of α-cyano-4β-benzylamino-crotonamide and 3-cyano- and 3-carbamido-4-benzyl-amino-2-pyridones.The principal product in the hydrolysis of the 1-phenyl derivative is 3-cyano-4-anilino-5-formyl-2-pyridone.Cyclization of the latter by heating in phosphorus oxychloride leads to 3-chloro-4-cyanobenzonaphthyridine.
