Chemistry of Heterocyclic Compounds p. 909 - 914 (1986)
Update date:2022-08-16
Topics:
Yalysheva, N.Z.
Solov'eva, N.P.
Chistyakov, V.V.
Sheinker, Yu.N.
Granik, V.G.
The hydrolysis of 1-substituted 5-cyano-6-(β-dimethylamino)vinyl-4-pyrimidinones in acidic media was studied.It was shown that the 1-benzyl derivative is converted to a mixture of α-cyano-4β-benzylamino-crotonamide and 3-cyano- and 3-carbamido-4-benzyl-amino-2-pyridones.The principal product in the hydrolysis of the 1-phenyl derivative is 3-cyano-4-anilino-5-formyl-2-pyridone.Cyclization of the latter by heating in phosphorus oxychloride leads to 3-chloro-4-cyanobenzo<1,6>naphthyridine.
View More
Contact:+86-519-86339586，13584329896
Address:Changzhou Scientific and Education Park
Jiangyin Tenghua Import&Export Co.,Ltd.
Contact:+86-510-86263875
Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China
website:http://www.acrospharmatech.com
Contact:+1-3234804688
Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong
HANGZHOU YUNUO CHEMICAL CO.,LTD
website:http://www.yunuochem.com
Contact:0571-83715115
Address:hangzhou
Hebei Kangtai Pharmaceutical Co.,Ltd
Contact:+86-0317-3512963
Address:Wugang Road,Mengcun of Cangzhou City,Hebei Province ,China
Doi:10.1021/jm00392a016
(1987)Doi:10.1007/BF00960415
(1991)Doi:10.1016/S0031-9422(00)82366-3
(1987)Doi:10.1002/anie.201603210
(2016)Doi:10.1021/ja01368a062
(1930)Doi:10.1002/ejoc.201001107
(2010)
