108963-20-8

Basic information

• Product Name: N,N'-DIBENZYL-3-AMINOPYRROLIDINE
• Synonyms: N-BENZYL-3-(BENZYLAMINO)PYRROLIDINE;N,N'-DIBENZYL-3-AMINOPYRROLIDINE;N,N'-dibenzyl-3-aminopyrrolidine95+%;N,1-Dibenzyl-3-pyrrolidinamine;N,N'-Dibenzyl-3-aminopyrrolidine
• CAS NO: 108963-20-8
• Molecular Formula: C18H22N2
• Molecular Weight: 266.38
• Product Categories: 3-Aminopyrrolidines;3-Aminopyrrolidines (Racemic)
• Mol File: 108963-20-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 385.9 °C at 760 mmHg
• Flash Point: 145 °C
• Appearance: /
• Density: 1.04
• Vapor Pressure: 3.68E-06mmHg at 25°C
• Refractive Index: 1.5680-1.5720
• CAS DataBase Reference: N,N'-DIBENZYL-3-AMINOPYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-DIBENZYL-3-AMINOPYRROLIDINE(108963-20-8)
• EPA Substance Registry System: N,N'-DIBENZYL-3-AMINOPYRROLIDINE(108963-20-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: 2735
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 108963-20-8(Hazardous Substances Data)

Usage

General Description

N,N'-Dibenzyl-3-aminopyrrolidine is a chemical compound that belongs to the class of organic compounds known as benzylic amines. These are organic compounds containing an amine group attached to a benzyl group. N,N'-DIBENZYL-3-AMINOPYRROLIDINE is not commonly found in nature and is primarily synthesized for use in laboratories and industries. It is often used as a chemical reagent in various chemical reactions. Its physical properties include a translucent appearance and a strong aroma. Like any other chemical, it should be handled carefully as it might cause irritation to the eyes, respiratory system, and skin.

InChI:InChI=1/C18H22N2/c1-3-7-16(8-4-1)13-19-18-11-12-20(15-18)14-17-9-5-2-6-10-17/h1-10,18-19H,11-15H2

Upstream product

• 100-52-7 benzaldehyde 
• 114715-39-8 (R)-1-benzyl-3-aminopyrrolidine 
• 18471-40-4 1-Benzyl-3-aminopyrrolidine 
• 57050-27-8 N-benzyl maleimide 
• 100-46-9 benzylamine 
• 38300-67-3 1,3,4-Tribromobutane 
• 124166-11-6 (S)-(1-benzyl-2,5-dioxo-pyrrolidin-3-yl)carbamic acid benzyl ester 
• 124223-92-3 (3S)-3-amino-1-benzylpyrrolidine-2,5-dione 
• 100-39-0 benzyl bromide 
• 114715-38-7 (3S)-1-benzyl-3-pyrrolidinamine 
• 145223-68-3 (S)-1-Benzyl-3-{[1-phenyl-meth-(E)-ylidene]-amino}-pyrrolidine-2,5-dione 

Downstream Products

• 953030-71-2 tert-butyl 3-{(3R)-3-[benzyl(cyclopropylcarbonyl)amino]pyrrolidin-1-yl}-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 953030-72-3 N-[(3R)-1-(8-azabicyclo[3.2.1]oct-3-yl)pyrrolidin-3-yl]-N-benzylcyclopropanecarboxamide 
• 952744-24-0 N-benzyl-N-[(3R)-pyrrolidin-3-yl]cyclopropanecarboxamide 
• 145223-70-7 (S)-N-Benzyl-N-((S)-1-benzyl-pyrrolidin-3-yl)-2-fluoro-2-phenyl-acetamide 
• 145223-78-5 (R)-N-Benzyl-N-((S)-1-benzyl-pyrrolidin-3-yl)-2-fluoro-2-phenyl-acetamide 

Relevant articles and documents

Design, synthesis, and multitargeted profiling of N-benzylpyrrolidine derivatives for the treatment of Alzheimer's disease

Multitarget molecular hybrids of N-benzyl pyrrolidine derivatives were designed, synthesized, and biologically evaluated for the treatment of Alzheimer's disease (AD). Among the synthesized compounds, 4k and 4o showed balanced enzyme inhibitions against c

CHEMICAL COMPOUNDS

The present invention provides compounds of formula (I) wherein R1 to R6 and m are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Mo

Handy access to chiral N,N'-disubstituted 3-aminopyrrolidines

A new and rapid synthesis of (S)-3-aminopyrrolidines Z is proposed from N-protected (S)-Asparagine. Basic cyclization of methyl N-Z-(S)-Asparaginate 1 followed by one-pot N-benzylation directly leads to (S)-aminosuccinimide 3 which, after cleavage of the