108990-72-3 Usage
Uses
Used in Pharmaceutical Synthesis:
5H-Cyclopentapyrimidin-2-amine, 6,7-dihydro(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, 5H-Cyclopentapyrimidin-2-amine, 6,7-dihydro(9CI) serves as a versatile reagent for the synthesis of a wide range of organic compounds. Its ability to participate in various chemical reactions, such as nucleophilic substitution, addition, and condensation, allows for the creation of diverse chemical entities with potential applications in various industries.
Used in Medicinal Chemistry Research:
5H-Cyclopentapyrimidin-2-amine, 6,7-dihydro(9CI) is also utilized in medicinal chemistry research as a starting material for the design and synthesis of novel drug candidates. Its unique chemical properties and potential for modification make it an attractive candidate for the development of new therapeutic agents with improved efficacy and selectivity.
Used in Drug Discovery:
In the drug discovery process, 5H-Cyclopentapyrimidin-2-amine, 6,7-dihydro(9CI) is employed as a potential lead compound for the identification and optimization of new drugs. Its unique structure and reactivity provide opportunities for the exploration of novel chemical space and the discovery of innovative therapeutic agents.
Used in Chemical Synthesis Process Development:
5H-Cyclopentapyrimidin-2-amine, 6,7-dihydro(9CI) is utilized in the development of efficient and scalable chemical synthesis processes. Its unique properties and reactivity make it a valuable component in the design of new synthetic routes and the optimization of existing processes, ultimately contributing to the advancement of chemical manufacturing and production techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 108990-72-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,9,9 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 108990-72:
(8*1)+(7*0)+(6*8)+(5*9)+(4*9)+(3*0)+(2*7)+(1*2)=153
153 % 10 = 3
So 108990-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H9N3/c8-7-9-4-5-2-1-3-6(5)10-7/h4H,1-3H2,(H2,8,9,10)
108990-72-3Relevant academic research and scientific papers
Efficient synthesis of 4- And 5-substituted 2-aminopyrimidines by coupling of β-Chlorovinyl Aldehydes and Guanidines
Komendantova, Anna S.,Komkov, Alexander V.,Volkova, Yulia A.,Zavarzin, Igor V.
, p. 4247 - 4254 (2018/08/24)
A general, practical, and simple synthesis of functionalized 2-aminopyrimidines starting from β-chlorovinyl aldehydes and amidines is reported. In the presence of potassium carbonate, various ketones have been efficiently transformed into the pyrimidine derivatives by a two-step sequence involving the Vilsmeier-Haack reaction followed by a condensation reaction with guanidines. The protocol is distinguished by operational simplicity, inexpensive reagents, and functional-group tolerance. In many cases, pure solid products can be obtained in high to excellent yields without using column chromatography. The synthetic value of the method was demonstrated by the efficient synthesis of steroidal pyrimidines and a precursor of the antitumor agents Imatinib and Mocetinostat.
