108990-72-3 Usage
General Description
5H-Cyclopentapyrimidin-2-amine, 6,7-dihydro- (9CI) is a chemical compound with the molecular formula C5H9N3. It is a derivative of cyclopentapyrimidine and is classified as a secondary amine. 5H-Cyclopentapyrimidin-2-amine, 6,7-dihydro- (9CI) is used in the synthesis of various pharmaceuticals and organic compounds. It may also have potential applications in the field of medicinal chemistry as a building block for the creation of new drugs. Its precise uses and properties, however, may vary depending on the specific application and chemical environment in which it is utilized.
Check Digit Verification of cas no
The CAS Registry Mumber 108990-72-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,9,9 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 108990-72:
(8*1)+(7*0)+(6*8)+(5*9)+(4*9)+(3*0)+(2*7)+(1*2)=153
153 % 10 = 3
So 108990-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H9N3/c8-7-9-4-5-2-1-3-6(5)10-7/h4H,1-3H2,(H2,8,9,10)
108990-72-3Relevant articles and documents
Efficient synthesis of 4- And 5-substituted 2-aminopyrimidines by coupling of β-Chlorovinyl Aldehydes and Guanidines
Komendantova, Anna S.,Komkov, Alexander V.,Volkova, Yulia A.,Zavarzin, Igor V.
, p. 4247 - 4254 (2018/08/24)
A general, practical, and simple synthesis of functionalized 2-aminopyrimidines starting from β-chlorovinyl aldehydes and amidines is reported. In the presence of potassium carbonate, various ketones have been efficiently transformed into the pyrimidine derivatives by a two-step sequence involving the Vilsmeier-Haack reaction followed by a condensation reaction with guanidines. The protocol is distinguished by operational simplicity, inexpensive reagents, and functional-group tolerance. In many cases, pure solid products can be obtained in high to excellent yields without using column chromatography. The synthetic value of the method was demonstrated by the efficient synthesis of steroidal pyrimidines and a precursor of the antitumor agents Imatinib and Mocetinostat.
