109013-31-2Relevant academic research and scientific papers
Acyl Migrations on 3(5)-Amino-pyrazole
Graubaum, Heinz
, p. 585 - 588 (2007/10/02)
3(5)-Amino-pyrazole 1 form 3 isomeric monoacylation products, 4-diacylation products and 3-triacylation products by reaction with electrophiles like cyanates, isocyanates or carboxylic and chlorides, respectively.Acyl migrations are observed depending on the reaction temperature and the structure of the acyl residue.The structures of the acyl derivatives of 3(5)-amino-pyrazole were characterized by nmr-spectroscopy.
CARBAMOYL DERIVATIVES OF UNSUBSTITUTED 3(5)-AMINOPYRAZOLE
Razvodovskaya, L. V.,Erikova, M. V.,Putsykina, E. B.,Negrebetskii, V. V.,Grapov, A. F.
, p. 1145 - 1149 (2007/10/02)
Unsubstituted 3(5)-aminopyrazole reacts with various isocyanates or dialkylcarbamoyl chloride to give products of monocarbamoylation at the nitrogen atoms of the heteroring, 3-amino- and 5-amino-1-carbamoylpyrazoles or their mixture, depending on the structure of the carbamoylating agent.For the 3-chlorophenylaminocarbonyl derivative we showed the possibility of the 1,2-transition of the carbamoyl group and calculated thermodynamic parameters of this process.Aryl isocyanates react with 3(5)-aminopyrazole under severe conditions to give products of dicarbamoylation of the heteroring.
Reactions with Diazoazoles, VIII. - Syntheses of Azolo-1,2,3,5-tetrazin-4(3H)-ones
Ege, Guenter,Gilbert, Karlheinz,Maurer, Kurt
, p. 1375 - 1396 (2007/10/02)
Azolo-1,2,3,5-tetrazin-4(3H)-ones 4 and 5 are formed by cycloaddition reactions of α-diazoazoles 2 with aryl or alkyl isocyanates 3a-p, respectively, as well as with diisocyanates 3q,r (Method A).Alternative syntheses for 4 are presented by diazoti
