109057-06-9Relevant academic research and scientific papers
Efficient and recyclable solid acid-catalyzed alkylation of active methylene compound via oxonium intermediate for atom economical synthesis of organic compounds
Naikwadi, Dhanaji R.,Bankar, Balasaheb D.,Ravi, Krishnan,Biradar, Ankush V.
, p. 3691 - 3703 (2021/06/12)
In the present work, we report the catalytic reaction of active methylene compounds with cyclic enol ethers and aryl acetals through oxonium intermediate under solvent-free conditions using heterogeneous solid acid catalysts. Among studied solid acid catalysts, Amberlyst-15 gave excellent yields (35–85%) of alkylated products. The catalyst showed broader substrate scope, and a recyclable catalytic cost-efficient approach of the alkylation was examined on the different types of cyclic enol ethers and aryl acetal.
Stereoselective synthesis of α-ylidene-β-dicarbonyl compounds: A mild PhI(OAc)2-mediated dehydrogenation process
Fan, Liyan,Chen, Wen,Tang, Kunshan,Wu, Dongbei
, p. 940 - 942 (2012/11/06)
PhI(OAc)2-mediated dehydrogenation of α-alkyl-β-dicarbonyl compound has been developed to afford α-ylidene-β- dicarbonyl compounds with high stereoselectivity under mild conditions. This process provides a complementary entry to stereoselectivity for the Knoevenagel reaction.
An efficient iodine-catalysed Knoevenagel condensation reaction in the presence of acetic anhydride
Li, Zhong-Xian,Liu, Xiao-Pei,Qiu, Zhen,Xu, Dan,Yu, Xue-Jun
experimental part, p. 35 - 36 (2011/04/24)
A mild, simple and efficient iodine catalysed system has been developed for the Knoevenagel condensation of 1,3-dicarbonyl compounds with various aromatic aldehydes in the presence of acetic anhydride. The reaction gave good to excellent yields for a broad range of substrates.
An efficient method for the selective iodination of ?±,?2- unsaturated ketones
Wang, Zihua,Yin, Guodong,Qin, Jing,Gao, Meng,Cao, Liping,Wu, Anxin
scheme or table, p. 3675 - 3681 (2009/06/18)
An efficient approach to ?±,?2-unsaturated ?±'-iodo ketones directly from ?±,?2-unsaturated ketones by selective iodination at the ?±'-position, without effect on the double bond and the activated benzene ring, in the presence of copper (II) oxide/iodine is described. The present method has the advantages of high yields, short reaction times, inexpensive reagents, mild reaction conditions, ease of manipulation, and the formation of cleaner products. ? Georg Thieme Verlag Stuttgart ?· New York.
A highly efficient preparative method of α-ylidene-β-diketones via AuIII-catalyzed acyl migration of propargylic esters
Wang, Shaozhong,Zhang, Liming
, p. 8414 - 8415 (2007/10/03)
A highly efficient synthesis of α-alkylidene or benzylidene-β-diketones from readily available propargylic esters has been developed. The proposed key transformation is a novel intramolecular acyl migration to nucleophilic AuIII-C(sp2/sup
