109103-45-9Relevant articles and documents
Metal-free synthesis of isatin oximes: Via radical coupling reactions of oxindoles with t -BuONO in water
Wei, Wen-Ting,Zhu, Wen-Ming,Ying, Wei-Wei,Wu, Yi,Huang, Yi-Ling,Liang, Hongze
, p. 5254 - 5257 (2017)
A metal-free method for the synthesis of isatin oximes was developed through the radical coupling reactions of oxindoles with t-BuONO. This protocol provides a practical and environmentally benign method for the construction of C-N bonds in water at room temperature without using any other reagents. The advantages of this strategy are its mild reaction conditions and clean procedure.