109210-19-7Relevant academic research and scientific papers
(C6F5)3B Catalyzed Chemoselective and ortho-Selective Substitution of Phenols with α-Aryl α-Diazoesters
Yu, Zhunzhun,Li, Yongfeng,Shi, Jiameng,Ma, Ben,Liu, Lu,Zhang, Junliang
, p. 14807 - 14811 (2016/11/23)
The development of an efficient method for the site-selective substitution of unprotected phenols has long been considered as an attractive but challenging task. Herein, we describe a highly chemo- and ortho-selective substitution reaction of phenols with α-aryl α-diazoacetates with commercially available (C6F5)3B as the catalyst. This reaction proceeds under simple and mild conditions with high efficiency, it features a wide substrate scope and can be easily scaled up.
General and practical one-pot synthesis of dihydrobenzosiloles from styrenes
Kuznetsov, Alexey,Gevorgyan, Vladimir
supporting information; experimental part, p. 914 - 917 (2012/05/05)
A one-pot synthesis of dihydrobenzosiloles from styrenes has been developed. The reaction involves the nickel-catalyzed hydrosilylation of styrene with diphenylsilane, followed by the iridium-catalyzed dehydrogenative cyclization. This method is efficient for both electron-rich and -deficient styrenes and exhibits good functional group tolerance, as well as excellent regioselectivity. The forming dihydrobenzosiloles can be efficiently converted into valuable benzosiloles or 2-hydroxyphenethyl alcohols.
A new regio- and stereoselective intermolecular Friedel-Crafts alkylation of phenolic substrates with aryl epoxides
Bertolini, Ferruccio,Crotti, Paolo,Macchia, Franco,Pineschi, Mauro
, p. 61 - 64 (2007/10/03)
A conceptually new regioselective and highly syn-stereoselective intermolecular Friedel-Crafts-type O-alkylation of phenols with aryl epoxides by the use of appropriately substituted aryl borates is reported. The carbon-carbon bond formation occurs in neutral and mild conditions without the need for external Lewis acids or transition metal catalysts.
