109269-89-8

Basic information

• Product Name: 5H-Pyrido[1,2-c]pyrrolo[1,2-a]pyrimidine,decahydro-5-pentyl-, (5S,6aR,11aS)-
• Synonyms: 5H-Pyrido[1,2-c]pyrrolo[1,2-a]pyrimidine,decahydro-5-pentyl-, [5S-(5a,6ab,11ab)]-; (+)-Tetraponerine 8; Tetraponerine 8
• CAS NO: 109269-89-8
• Molecular Formula: C16H30 N2
• Molecular Weight: 250.428
• Mol File: 109269-89-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5H-Pyrido[1,2-c]pyrrolo[1,2-a]pyrimidine,decahydro-5-pentyl-, (5S,6aR,11aS)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Pyrido[1,2-c]pyrrolo[1,2-a]pyrimidine,decahydro-5-pentyl-, (5S,6aR,11aS)-(109269-89-8)
• EPA Substance Registry System: 5H-Pyrido[1,2-c]pyrrolo[1,2-a]pyrimidine,decahydro-5-pentyl-, (5S,6aR,11aS)-(109269-89-8)

Safety Data

• Hazardous Substances Data: 109269-89-8(Hazardous Substances Data)

Usage

Chemical Structure


Classification

Synthetic cannabinoid compound

Biological Activity

Acts as a potent and selective agonist of the cannabinoid receptor CB1

Pharmacological Effects

Analgesic properties
Neuroprotective effects
Anti-inflammatory effects

Therapeutic Applications

Treatment of chronic pain
Potential use in neurodegenerative disorders
Potential for managing inflammatory diseases

Research Applications

Investigation of the endocannabinoid system
Understanding its role in physiological and pathological processes

Upstream product

• 123-75-1 pyrrolidine 
• 505-18-0 2,3,4,5-tetrahydropyridine 
• 110-43-0 n-pentyl methyl ketone 

Relevant articles and documents

A Highly Active System for the Metal-Free Aerobic Photocyanation of Tertiary Amines with Visible Light: Application to the Synthesis of Tetraponerines and Crispine A

A highly efficient metal-free catalytic system for the aerobic photocyanation of tertiary amines with visible light is reported. The use of air as terminal oxidant offers an improved safety profile compared with pure oxygen, the used compact fluorescent lamp (CFL) light sources are highly economical, and no halogenated solvents are required. This system not only proves to be effective for a wide variety of trialkylamines, pharmaceuticals, and alkaloids but remarkably also allows the lowest catalyst loading (0.00001 mol % or 0.1 ppm) ever reported for an organic dye. Bruylants reactions and C-alkylation/decyanations were performed on the obtained α-aminonitriles to demonstrate the postfunctionalization of complex molecules. The catalytic system is furthermore applied in the short and effective syntheses of the alkaloids (±)-crispine A and the tetraponerines T7 and T8.