109287-33-4Relevant academic research and scientific papers
Synthesis of 5-[bromo(aryl)methyl]-2,2-dimethyl-1,3-oxazolidin-4-ones
Mamedov,Mamedova,Khikmatova,Krivolapov,Litvinov
, p. 1260 - 1267 (2016)
A Darzens condensation of α-chloroacetamide with aromatic aldehydes furnished a series of 3-aryl-2,3-epoxypropionamides, which were further converted to 5-[bromo(aryl)methyl]-2,2-dimethyl-1,3-oxazolidin-2-ones.
New and efficient synthesis of 3-arylquinazolin-4(1H)-ones and biologically important N-fused tetracycles based on N-(2-carboxyphenyl)oxalamide
Mamedov, Vakhid A.,Mamedova, Vera L.,Syakaev, Victor V.,Gubaidullin, Aidar T.,Voronina, Julia K.,Kushatov, Temur A.,Korshin, Dmitry E.,Samigullina, Aida I.,Tanysheva, Ekaterina G.,Kh. Rizvanov, Il'dar,Latypov, Shamil K.
, (2021/09/28)
A novel clean, one-pot syntheses of 3-arylquinazolin-4(3H)-ones and quinoxalino[2,1-b]quinazoline-6,12(5H)-diones via PPA-mediated coupling of N-(2-carboxyphenyl)oxalamides with arylamines and 1,2-benzenediamines have been developed. Under mild reaction conditions with use of Na2S2O4 the benzimidazo[2,1-b]quinazolin-12-ones were achieved in good yield from 3-(2-nitrophenyl)quinazolin-4-ones.
A novel acid-catalyzed rearrangement of 2-substituted-3-(2-nitrophenyl)oxiranes for the synthesis of di- and mono-oxalamides
Mamedov, Vakhid A.,Mamedova, Vera L.,Khikmatova, Gul'Nas Z.,Mironova, Ekaterina V.,Krivolapov, Dmitry B.,Bazanova, Olga B.,Chachkov, Denis V.,Katsyuba, Sergey A.,Rizvanov, Il'Dar Kh,Latypov, Shamil K.
, p. 27885 - 27895 (2016/03/30)
A novel one-pot synthetic approach to N1-(2-carboxyaryl)-N2-(aryl or H)oxalamides from 3-(2-nitroaryl)oxirane-2-carboxamides via the classical Meinwald rearrangement and a new rearrangement sequence has been developed. The methodology is applicable to the synthesis of N-(2-carboxyphenyl)aryloxalmonoamides from (3-(2-nitrophenyl)oxiran-2-yl)(aryl)methanones. The method is operationally simple and high yielding, thus providing a new useful formula for both anthranilic acid derivatives and oxalamides.
