1092970-75-6Relevant academic research and scientific papers
An effective and general method for the highly regioselective synthesis of 1-phenylpyrazoles from β-enaminoketoesters, tandem Blaise-acylation adducts
Ko, Young Ok,Chun, Yu Sung,Park, Cho-Long,Kim, Youngmee,Shin, Hyunik,Ahn, Sungho,Hong, Jongki,Lee, Sang-Gi
supporting information; experimental part, p. 1132 - 1136 (2009/05/30)
An effective and general route for the regioselective synthesis of 1-phenylpyrazoles has been developed from β-enaminoketoesters prepared by tandem Blaise-acylation. This method is applicable to a very broad range of substrates, generating a diverse set o
The first chemoselective tandem acylation of the Blaise reaction intermediate: A novel method for the synthesis of α-acyl-β-enamino esters, key intermediate for pyrazoles
Sung Chun, Yu,Kon Lee, Ki,Ok Ko, Young,Shin, Hyunik,Lee, Sang-Gi
supporting information; experimental part, p. 5098 - 5100 (2009/03/11)
The Blaise reaction intermediate, a zinc bromide complex of β-enamino ester, could be activated in situ by addition of a stoichiometric or catalytic amount of n-BuLi to allow chemoselective tandem C2-acylation providing α-acyl-β-enamino esters, which are
