155934-55-7Relevant articles and documents
A chiron approach to the total synthesis of cytotoxic (+)-muricatacin and (+)-5-epi-muricatacin from d-ribose
Ghosal, Partha,Kumar, Vikas,Shaw, Arun K.
, p. 41 - 44 (2010)
A chiron approach strategy toward the total synthesis of (+)-muricatacin and (+)-5-epi-muricatacin starting from commercially available and inexpensive d-ribose through the key intermediate (S)-5-((R)-1-hydroxyallyl)furan-2(5H)-one has been disclosed.
Stereoselective Total Synthesis of Arundinolides A and B
Chang, Caizhu,Dong, Zhi-Bing,Du, Yuguo,Geng, Jialin,Liu, Jun,Liu, Yinxin
, p. 1576 - 1584 (2020)
The efficient and enantioselective syntheses of arundinolides A and B have been accomplished for the first time from chiral pool methyl-2,3- O -isopropylidene-β- d -ribofuranoside and d -ethyl lactate. The key features of the total synthesis are intramolecular crotonyl migration and NaBH 4 -CuCl catalyzed regioselective reduction and cross-metathesis reaction.
Total Synthesis of Meayamycin and O-Acyl Analogues
Boger, Dale L.,Chanda, Prem B.,Chowdari, Naidu S.,Gangwar, Sanjeev,Gartshore, Christopher,Momirov, Jelena,Sarkar, Anindya,Tadano, Shinji,Vite, Gregory D.,Zhang, Qian
, (2020/11/18)
A short, scalable total synthesis of meayamycin is described by an approach that entails a longest linear sequence of 12 steps (22 steps overall) from commercially available chiral pool materials (ethyl l-lactate, BocNH-Thr-OH, and d-ribose) and introduces the most straightforward preparation of the right-hand subunit detailed to date. The use of the approach in the divergent synthesis of a representative series of O-acyl analogues is exemplified.
Synthesis of N-alkyl substituted iminosugars from D-ribose
Wang, Haibo,Pan, Yang,Tang, Qin,Zou, Wei,Shao, Huawu
, p. 73 - 75 (2017/10/26)
An effective and facile method for the synthesis of N-alkylated hydroxylpyrrolidine and hydroxylpiperidine is described. A number of N-alkyl substituted iminosugars were prepared using iodine-induced intramolecular cyclization of acyclic alkenylamines as key step.