109337-51-1Relevant academic research and scientific papers
Physiological activity of Chinese Lichen (Gyrophora esculenta) component, methyl 2,4-dihydroxy-6-methylbenzoate and the related compounds
Wu, Shuhsien,Zhao, Zhendong,Okada, Yoshiharu,Watanabe, Yoshiyuki,Takahata, Toshiyuki,Inoue, Toshio,Otsubo, Eiji,Wang, Jing,Lu, Yanju,Nomura, Masato
, p. 702 - 708 (2014)
It was confirmed that there was a higher expression of antioxidant potential in methyl 2,4-dihydroxy-6-methylbenzoate (orsellinic acid methyl ester) (2), which was isolated from methanol extract oil of Chinese lichen Gyrophora esculenta rather than from commercialized ascorbic acid. Taking this into account, 4 types of compounds-(4-7) which are known to be related to compound (2)-have been synthesized by using 2,4-dihydroxy benzoic acid (3) as starting material. After that, some physiological activity tests on these compounds have been conducted in the following aspects: antioxidant potential, cytotoxicity, cytokine suppressant effect and histamine liberation inhibition and the effects have been evaluated, respectively. The result shows that (2) and methyl 2,4-dihydroxybenzoate (4) showed high radical expression in both antioxidant potential and histamine liberation inhibition. It was also found that none of these compounds expresses cytotoxicity.
Synthesis of Mesomorphic Derivatives of Methyl 2,4-Dihydroxybenzoate and Spectral and Luminescence Properties of Their Lanthanide Complexes
Novikova,Kilimenchuk,Kondrat’eva,Teslyuk,Zheltvai
, p. 2564 - 2571 (2018)
The derivatives of methyl 2,4-dihydroxybenzoate containing fragments of different organic acids in position 4 have been synthesized. Their mesomorphic properties have been investigated. Lanthanide complexes of the prepared compounds have been obtained. Th
Methods of protection against emesis in mammals by administration of a heterocyclic benzamide
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, (2008/06/13)
The heterocyclic benzamides of this invention are particularly effective for the treatment of emesis in mammals. For example, when they are administered to dogs in relatively small dosage, they afford 100% protection against vomiting. They are also non-toxic in dosages for effecting complete control of vomiting.
