109347-45-7

Basic information

• Product Name: 2-(4-TERT-BUTYLPHENYL)ACETALDEHYDE
• Synonyms: 2-(4-TERT-BUTYLPHENYL)ACETALDEHYDE;(4-tert-Butylphenyl)acetaldehyde
• CAS NO: 109347-45-7
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25484
• Mol File: 109347-45-7.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 257.8 °C at 760 mmHg
• Flash Point: 115.6 °C
• Appearance: /
• Density: 0.946 g/cm³
• CAS DataBase Reference: 2-(4-TERT-BUTYLPHENYL)ACETALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-TERT-BUTYLPHENYL)ACETALDEHYDE(109347-45-7)
• EPA Substance Registry System: 2-(4-TERT-BUTYLPHENYL)ACETALDEHYDE(109347-45-7)

Safety Data

• Hazardous Substances Data: 109347-45-7(Hazardous Substances Data)

Usage

Physical state

Clear and colorless liquid The compound appears as a transparent and colorless liquid under normal conditions.

Odor

Fruity It has a pleasant and fruity smell.

Usage

Fragrance and flavor ingredient It is commonly used to add sweet, floral, and green notes to various products, such as perfumes, dyes, and pharmaceuticals.

Synthesis

Used in the production of pharmaceuticals, dyes, and perfumes The compound serves as a key ingredient in the creation of these products.

Safety concerns

Flammable The compound can easily catch fire, so it should be stored and handled with caution.

Safety concerns

Skin and eye irritation Contact with the skin or eyes may cause irritation, so proper protective measures should be taken when handling the compound.

Upstream product

• 939-97-9 4-tert-Butylbenzaldehyde 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 1746-23-2 4-tert-Butylstyrene 
• 5406-86-0 2-(4-tert-butylphenyl)ethanol 
• 80-54-6 lilial 
• 18127-01-0 3-(4-tert-butylphenyl)propionaldehyde 
• 772-38-3 4-tert-Butylphenylacetylene 

Downstream Products

• 57479-16-0 3-(4-(tert-butyl)phenyl)quinoline 
• 1400648-43-2 2-[2-(4-tert-Butylphenyl)ethyl]-N-[4-(3-cyclopentylpropyl)-2-fluorophenyl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide 
• 1400650-24-9 2-[2-(4-tert-butylphenyl)ethyl]-N-[2-fluoro-4-(hexyloxy)phenyl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide 
• 1400650-20-5 2-[2-(4-tert-butylphenyl)ethyl]-N-[2-fluoro-4-(4-phenylbutoxy)phenyl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide 

Relevant articles and documents

Highly active in situ catalysts for anti-Markovnikov hydration of terminal alkynes

(Diagram presented) The anti-Markovnikov hydration of terminal alkynes to give aldehydes is catalyzed by complexes derived in situ from air-stable [CpRu(η6-naphthalene)]PF6 (C) and 6-aryl-2- diphenylphosphinopyridines (L). Ligands L are readily available from a modular synthesis. Increasing the size of the ligand C-6 aryl group in the order R = Ph mesityl 2,4,6-triisopropylphenyl (2,4,6-triphenyl)phenyl gave hydration catalysts of highest known activity.

B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of: In situ -formed enamines

A highly efficient B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of in situ-formed enamines in the presence of water and pinacolborane was developed. Regioselective β-deuteration of tertiary amines was achieved with high chemo- and regioselectivity. D2O was used as a readily available and cheap source of deuterium. Mechanistic studies indicated that B(C6F5)3 could activate water to promote the protonation and reduction of enamines. This journal is

Copper-Catalyzed Ring-Opening/Reconstruction of Anthranils with Oxo-Compounds: Synthesis of Quinoline Derivatives

A copper-catalyzed protocol for the construction of various 2-aryl(alkyl)-3-acylquinolines or 3-arylquinolines using readily available anthranils and 1,3-diketones or aldehydes as starting materials is reported herein. Dioxygen as the sole oxidant and hexafluoroisopropanol as the solvent play an important role in both procedures. This ring-opening/reconstruction strategy involving N-O bond cleavage and C-N/C-C bond formation features high yields and broad substrate scope.