109371-17-7 Usage
Description
2,4-Dichloro-3,5,6-trimethylpyridine is a chemical compound with the molecular formula C7H8Cl2N. It is a derivative of pyridine, characterized by the presence of two chlorine atoms at the 2nd and 4th positions and three methyl groups at the 3rd, 5th, and 6th positions. 2,4-DICHLORO-3,5,6-TRIMETHYLPYRIDINE is known for its insecticidal properties and is commonly used in the production of pharmaceuticals and agrochemicals.
Uses
Used in Agrochemical Industry:
2,4-Dichloro-3,5,6-trimethylpyridine is used as an active ingredient in insecticides for controlling pests in agriculture. Its insecticidal properties make it effective in protecting crops from various insect infestations, thereby ensuring higher crop yields and quality.
Used in Pharmaceutical Industry:
2,4-Dichloro-3,5,6-trimethylpyridine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be incorporated into the development of new drugs with potential therapeutic applications.
However, it is important to note that 2,4-Dichloro-3,5,6-trimethylpyridine is a highly reactive compound and must be handled with caution due to its potential health and environmental hazards. Proper safety measures and guidelines should be followed during its production, storage, and use to minimize any risks associated with its handling.
Check Digit Verification of cas no
The CAS Registry Mumber 109371-17-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,3,7 and 1 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 109371-17:
(8*1)+(7*0)+(6*9)+(5*3)+(4*7)+(3*1)+(2*1)+(1*7)=117
117 % 10 = 7
So 109371-17-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H9Cl2N/c1-4-6(3)11-8(10)5(2)7(4)9/h1-3H3
109371-17-7Relevant articles and documents
Synthesis of 4-methoxy-2,3,5-trimethylpyridine: a specific building block for compounds with gastric-acid inhibiting activity.
Mittelbach,Schmidt,Uray,Junek,Lamm,Ankner,Br?ndstr?m,Simonsson
, p. 524 - 529 (2007/10/02)
A new synthesis of 4-methoxy-2,3,5-trimethylpyridine (2), an important building block for the preparation of gastric-acid inhibiting compounds, is described. Condensation of ethyl 3-amino-2-methyl-2-butenoate (3) and diethyl 2-methylmalonate (4) gives 4-hydroxy-3,5,6-trimethyl-2(1H)-pyridone 5. Reaction of 5 with phosphoryl chloride affords 2,4-dichloro-3,5,6-trimethylpyridine (9a), which, upon hydrogenolysis with palladium on charcoal, gives 2,3,5-trimethylpyridine (10). However, selective hydrogenolysis in acidic solution yields 4-chloro-2-3-5-trimethylpyridine (11). Substitution of the chlorine in 11 with methoxide ion gives 4-methoxy-2,3,5-trimethylpyridine (2), which can be oxidized to the corresponding N-oxide (13). This constitutes a new and efficient route to compound 2 in an overall yield of 43%.
