109420-85-1

Basic information

• Product Name: 5'-O-(4,4'-dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine
• Synonyms: 5'-O-(4,4'-dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine
• CAS NO: 109420-85-1
• Molecular Weight: 751.836
• Mol File: 109420-85-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5'-O-(4,4'-dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4,4'-dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine(109420-85-1)
• EPA Substance Registry System: 5'-O-(4,4'-dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine(109420-85-1)

Safety Data

• Hazardous Substances Data: 109420-85-1(Hazardous Substances Data)

Upstream product

• 951-77-9 2'-Deoxycytidine 
• 87424-19-9 N-Fmoc-dC 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 887620-21-5 3'-O-(N,N-diisopropylamino)phosphinoformic acid β-(diphenylmethylsilyl)ethyl ester 5'-O-di-p-anisylphenylmethyl-N4-(9-fluorenylmethyloxycarbonyl)-2'-deoxycytidine 
• 127845-02-7 5'-O-(4,4'-dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine-3'-O-(methyl N,N-diisopropylamino)phosphoramidite 
• 109389-33-5 5'-O-(4,4'-Dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine 3'-O-<2-cyanoethyl-N,N-diisopropylphosphoramidite> 

Relevant articles and documents

The 9-fluorenylmethoxycarbonyl (Fmoc) group and its use in oligonucleotide synthesis

The introduction of the base-labile 9-fluorenylmethoxycarbonyl (Fmoc) group into the exocyclic amino function of 2'-deoxynucleosides and their dimethoxytritylation and phosphitylation is described. The resulting key intermediates were investigated in the

Synthesis of Oligonucleotides Containing Site-Specific Carcinogen Adducts. Preparation of the 2-Cyanoethyl N,N-Diisopropylphosphoramidite of N-(2'-Doexyguanosin-8-yl)-2-(acetylamino)fluorene with Fmoc as the Base-Protecting Group

A 9-fluorenylmethoxycarbonyl (Fmoc) group was used to protect the exocyclic amine on the modified guanine of N-(2'-deoxyguanosin-8-yl)-2-(acetylamino)fluorene (dG-C8-AAF) so that oligonucleotides containing a site-specific AAF adduct could be prepared.Rea