109389-33-5

Basic information

• Product Name: 5'-O-(4,4'-Dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine 3'-O-<2-cyanoethyl-N,N-diisopropylphosphoramidite>
• Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine 3'-O-<2-cyanoethyl-N,N-diisopropylphosphoramidite>
• CAS NO: 109389-33-5
• Molecular Weight: 952.056
• Mol File: 109389-33-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5'-O-(4,4'-Dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine 3'-O-<2-cyanoethyl-N,N-diisopropylphosphoramidite>(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4,4'-Dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine 3'-O-<2-cyanoethyl-N,N-diisopropylphosphoramidite>(109389-33-5)
• EPA Substance Registry System: 5'-O-(4,4'-Dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine 3'-O-<2-cyanoethyl-N,N-diisopropylphosphoramidite>(109389-33-5)

Safety Data

• Hazardous Substances Data: 109389-33-5(Hazardous Substances Data)

Upstream product

• 102691-36-1 N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite 
• 109420-85-1 5'-O-(4,4'-dimethoxytrityl)-N⁴-(9-fluorenylmethoxycarbonyl)-2'-deoxycytidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 951-77-9 2'-Deoxycytidine 
• 87424-19-9 N-Fmoc-dC 

Relevant articles and documents

The 9-fluorenylmethoxycarbonyl (Fmoc) group and its use in oligonucleotide synthesis

The introduction of the base-labile 9-fluorenylmethoxycarbonyl (Fmoc) group into the exocyclic amino function of 2'-deoxynucleosides and their dimethoxytritylation and phosphitylation is described. The resulting key intermediates were investigated in the

Solid phase synthesis of a model nucleopeptide with a phosphodiester bond between the 5′ end of a trinucleotide and a serine residue

The model nucleopeptide Boc-Ser(pTCT)-NHcHex has been assmbled on a polystyrene solid support using the phosphite triester approach. Fmoc and cyanoethyl groups have been used to protect the exocyclic amine of cytosine and phosphate groups respectively. Fi