109458-82-4

Upstream product

• 286-20-4 cyclohexane-1,2-epoxide 
• 73391-84-1 sodium 1,3-diphenyl-2-azapropenide 
• 50899-27-9 (3aS*,7aS*)-3-phenyl-3a,4,5,6,7,7a-hexahydrobenzo[d]isoxazole 

Downstream Products

• 128258-96-8 cis-4e-phenyl-5,6-tetramethylenetetrahydro-1,3-oxazine-2-thione 
• 109458-81-3 cis-2,4-diphenyl-trans-4a,8a-perhydrobenz-1,3-oxazine 
• 132287-32-2 3-p-Chlorophenyl-5t-phenyl-2-oxa-4-aza-1r,6c-bicyclo<4.4.0>dec-3-ene 
• 132287-26-4 3-p-Chlorophenyl-5c-phenyl-2-oxa-4-aza-1r,6c-bicyclo<4.4.0>dec-3-ene 
• 132287-27-5 5c-Phenyl-2-oxa-4-aza-1r,6c-bicyclo<4.4.0>decan-3(4H)-one 
• 132287-32-2 3-p-Chlorophenyl-5c-phenyl-2-oxa-4-aza-1r,6c-bicyclo<4.4.0>dec-3-ene 

Relevant academic research and scientific papers

PHENYL-SUBSTITUTED CYCLOPENTANE- AND CYCLOHEXANE-cis-FUSED-1,3-OXAZINES AND -1,4-OXAZEPINONES. PRREPARATION AND STEREOCHEMICAL STUDY

The cycloadditions of cyclopentene and cyclohexene with benzonitrile oxide (BNO) yielded isoxazolines 1 and 2, which were reduced to 1,3-aminoalcohols 3 and 4 with LAH and cyclized to cycloalkane-cis-condensed 4-phenyl-1,3-oxazines 6 and 7a,b.From the ami

The Reaction of Sodium 1,3-Diphenyl-2-azapropenide with 1,2-Epoxycyclohexane

Ring opening of 1,2-epoxycyclohexane by the title aza-allylic anion afforded a mixture of anions, the quenching and subsequent hydrolysis of which gave rise to trans-2-(α-aminobenzyl)cyclohexanol (10) and benzylamine as the basic fraction, and to either 1-benzoylcyclohexene (11) or trans-2-benzoylcyclohexanol (12), cis-2-benzoylcyclohexanol (14), and benzaldehyde as the neutral fraction: the type of ketone obtained depended upon the hydrolytic conditions.The perhydrobenzoxazine (7) was shown to be the precursor of compound (10).Sodium 1,3-diphenyl-2-azapropenide thus behaved both as an α-benzylamine carbanion equivalent and as a benzoyl anion equivalent.