109458-81-3Relevant academic research and scientific papers
The Reaction of Sodium 1,3-Diphenyl-2-azapropenide with 1,2-Epoxycyclohexane
Bradamante, Silvia,Ferraccioli, Raffaella,Pagani, Giorgio A.
, p. 515 - 518 (2007/10/02)
Ring opening of 1,2-epoxycyclohexane by the title aza-allylic anion afforded a mixture of anions, the quenching and subsequent hydrolysis of which gave rise to trans-2-(α-aminobenzyl)cyclohexanol (10) and benzylamine as the basic fraction, and to either 1-benzoylcyclohexene (11) or trans-2-benzoylcyclohexanol (12), cis-2-benzoylcyclohexanol (14), and benzaldehyde as the neutral fraction: the type of ketone obtained depended upon the hydrolytic conditions.The perhydrobenzoxazine (7) was shown to be the precursor of compound (10).Sodium 1,3-diphenyl-2-azapropenide thus behaved both as an α-benzylamine carbanion equivalent and as a benzoyl anion equivalent.
