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5H-CHROMENO[4,3-D]PYRIMIDIN-2-AMINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 109466-23-1 Structure
  • Basic information

    1. Product Name: 5H-CHROMENO[4,3-D]PYRIMIDIN-2-AMINE
    2. Synonyms: 5H-CHROMENO[4,3-D]PYRIMIDIN-2-AMINE;5H-CHROMENO[4,3-D]PYRIMIDIN-2-YLAMINE
    3. CAS NO:109466-23-1
    4. Molecular Formula: C11H9N3O
    5. Molecular Weight: 199.21
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 109466-23-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5H-CHROMENO[4,3-D]PYRIMIDIN-2-AMINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5H-CHROMENO[4,3-D]PYRIMIDIN-2-AMINE(109466-23-1)
    11. EPA Substance Registry System: 5H-CHROMENO[4,3-D]PYRIMIDIN-2-AMINE(109466-23-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 109466-23-1(Hazardous Substances Data)

109466-23-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 109466-23-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,4,6 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 109466-23:
(8*1)+(7*0)+(6*9)+(5*4)+(4*6)+(3*6)+(2*2)+(1*3)=131
131 % 10 = 1
So 109466-23-1 is a valid CAS Registry Number.

109466-23-1Downstream Products

109466-23-1Relevant articles and documents

New polycyclic pyrimidine derivatives with antiplatelet in vitro activity: Synthesis and pharmacological screening

Bruno, Olga,Schenone, Silvia,Ranise, Angelo,Bondavalli, Francesco,Barocelli, Elisabetta,Ballabeni, Vigilio,Chiavarini, Milena,Bertoni, Simona,Tognolini, Massimiliano,Impicciatore, Mariannina

, p. 629 - 636 (2007/10/03)

The preparation and the pharmacological screening of novel anti-aggregatory/antiphlogistic polycyclic pyrimidine derivatives are described. The compounds were developed starting from bioactive 2-aminobenzopyranopyrimidine derivatives in order to assess the importance of the benzopyrano[4,3-d]pyrimidine structure and the role of an amino basic moiety in position 2. Antiplatelet activity was assessed in vitro against ADP and arachidonic acid-induced aggregation in guinea-pig plasma. Anti-inflammatory/analgesic/antipyretic activities were studied in rat paw oedema, mouse writhing test and E coli-induced rat fever. Ulcerogenic and gastroprotective effects were also investigated in vivo on rat gastric mucosa. Among the tested compounds, the 5-substituted benzopyranopyrimidine derivatives 3d and 4d proved to be the most active antiplatelet agents as potent as acetylsalicylic acid against arachidonic acid-stimulated aggregation. Furthermore the 2-methylthio derivative 4d was endowed with greater efficacy against ADP aggregation suggesting that additional non-TXA2 dependent mechanisms are involved in its biological activity. Orally administered at 100mgkg-1 in rats this latter compound displayed antiphlogistic acitivity comparable to indomethacin (10 mg kg -1) coupled with an unusual gastroprotective effect on ethanol-induced ulcers. In conclusion, these findings indicate that the 5-pyrrolidino-2-methylthiobenzopyrano[4,3-d]pyrimidine 4d fulfils the chemical requirements to exhibit antiplatelet activity associated with gastroprotective effect. Copyright

Reactivite de β-enaminones cycliques. II. Cyclocondensation directe d'amidines, d'hydrazines et de l'hydroxylamine sur la pyrrolidinomethylene-3 chromanone-4

Graffe, Bernadette,Sacquet, Marie-Claude,Bellassoued-Fargeau, Marie-Claude,Maitte, Pierre

, p. 1753 - 1756 (2007/10/02)

The reaction of pyrrolidinomethylenechromanone 1 with guanidine and amidines gave benzopyrannopyrimidines 5 in good yields.Treatment of enaminone 1 with hydroxylamine in the presence of hydrochloric acid afforded the isoxazole 9.When hydrazine and phenylh

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