109495-50-3Relevant academic research and scientific papers
Cytotoxic homoleptic Ti(iv) compounds of ONO-type ligands: synthesis, structures and anti-cancer activity
Manne, Rajesh,Miller, Maya,Duthie, Andrew,Guedes Da Silva, M. Fátima C.,Tshuva, Edit Y.,Basu Baul, Tushar S.
, p. 304 - 314 (2019)
Eight Ti(iv) compounds 1-8, of the type [Ti(Ln)2] where Ln is a variously substituted dianionic tridentate acylhydrazone, were synthesized by reacting the appropriate hydrazide with 2-hydroxybenzaldehyde or 2′-hydroxyaceto
Regioselective quadruple domino aldolization/aldol condensation/Michael/ SNAr-cyclization: Construction of hexacyclic indeno-fused C-nor-D-homo-steroid frameworks
Chanda, Tanmoy,Chowdhury, Sushobhan,Ramulu, B. Janaki,Koley, Suvajit,Jones, Raymond C.F.,Singh, Maya Shankar
, p. 2190 - 2194 (2014/03/21)
An operationally simple and highly atom-economic anionic quadruple domino reaction sequence for the synthesis of hexacyclic indeno-fused naphthalene/quinoline molecules having structural resemblance with the C-nor-D-homo-steroid nucleus has been developed. Promoter and solvent specificity, regioselectivity and mechanistic details were experimentally established. Catalyst concentration and solvent dependent switching of domino steps creating four new C-C bonds are discussed.
SALICYLIC ACID HYDRAZONES AS INHIBITORS OF THE ERK MAPKINASE PATHWAY AND FOR THE TREATMENT OF CANCER
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Page/Page column 34-35, (2008/06/13)
The present invention includes methods of using certain salicylic acid hydrazones as inhibitors of cancer cell proliferation and/or survival and/or clonogenic cancer cell proliferation and/or survival. In particular, the compounds of the invention are use
