1095010-48-2 Usage
Uses
Used in Organic Synthesis:
1-Boc-5-Hydroxypiperidine-3-carboxylic Acid is used as a key intermediate in the synthesis of various organic compounds due to its unique structure and reactivity.
Used in Pharmaceutical Research:
1-Boc-5-Hydroxypiperidine-3-carboxylic Acid is used as a building block in the development of new pharmaceuticals, as it can be incorporated into the molecular structures of potential drug candidates.
Used in Drug Discovery:
1-Boc-5-Hydroxypiperidine-3-carboxylic Acid is used as a starting material in the discovery of new drugs, as its versatile properties allow for the exploration of various chemical reactions and modifications.
Used in Bioactive Molecule Synthesis:
1-Boc-5-Hydroxypiperidine-3-carboxylic Acid is used as a component in the synthesis of bioactive molecules, which have potential applications in medicine, agriculture, and other fields.
Used in Protecting Group Chemistry:
1-Boc-5-Hydroxypiperidine-3-carboxylic Acid is used as a model compound for studying the use of the tert-butoxycarbonyl group as a protecting group for amines in organic synthesis, which is crucial for the selective modification of complex molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1095010-48-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,5,0,1 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1095010-48:
(9*1)+(8*0)+(7*9)+(6*5)+(5*0)+(4*1)+(3*0)+(2*4)+(1*8)=122
122 % 10 = 2
So 1095010-48-2 is a valid CAS Registry Number.
1095010-48-2Relevant academic research and scientific papers
NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND
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Paragraph 0396-0399, (2016/08/29)
The present invention provides a compound represented by the following formula (I) or its pharmaceutically acceptable salt: [wherein, R1 represents optionally substituted C1-4 alkyl, n shows integer of 1 to 4, R2 represents optionally substituted C1-4 alkyl or hydrogen atom, R3 represents optionally substituted C1-4 alkyl, R4a, R4b, R4c, and R4d, similarly or differently, represent optionally substituted C6-14 aryl, optionally substituted C1-4 alkyl, or hydrogen atom and the like, A represents optionally substituted C6-14 aryl or optionally substituted 5 to 11 membered heteroaryl].
1,5-Substituted nipecotic amides: Selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability
DeNinno, Michael P.,Wright, Stephen W.,Visser, Michael S.,Etienne, John B.,Moore, Dianna E.,Olson, Thanh V.,Rocke, Benjamin N.,Andrews, Melissa P.,Zarbo, Cynthia,Millham, Michele L.,Boscoe, Brian P.,Boyer, David D.,Doran, Shawn D.,Houseknecht, Karen L.
, p. 3095 - 3098 (2011/06/24)
The first highly potent and selective PDE8 inhibitors are disclosed. The initial tetrahydroisoquinoline hit was transformed into a nipecotic amide series in order to address a reactive metabolite issue. Reduction of lipophilicity to address metabolic liab