109513-33-9Relevant academic research and scientific papers
Design of triple helix forming C-glycoside molecules
Li, Jian-Sen,Fan, Yun-Hua,Zhang, Yi,Marky, Luis A.,Gold, Barry
, p. 2084 - 2093 (2007/10/03)
The modeling, synthesis, and characterization of oligomers containing 2-aminoquinazolin-5-yl 2′-deoxynucleotide residues are reported. The 2-aminoquinazoline residues sequence specifically bind via Hoogsteen base pairing as a third strand in the center of
Polyaza heterocycles. Part 3. Halogenation of 1-substituted quinoxalinocinnolines: mechanistic implications
Harvey, Ian W.,Smith, David M.,White, Charles R.
, p. 1699 - 1704 (2007/10/03)
Since it has been proposed that halogenation of quinoxalinocinnolines at C-10, using hydrogen chloride or bromide in chloroform, occurs through initial protonation of the substrate at N-12, attempts have been made to inhibit this protonation by the introduction of an additional substituent at C-1.Where this substituent is chloro, bromo or methyl, chlorination still occurs preferentially at C-10, although the yield and the reaction rate decrease along the series, lending weight to the mechanistic proposal.
Acid-catalysed Cyclisation of o-Sulphonamido Ketene Dithioacetal S-Oxides: A Novel Synthesis of the Indole Ring System
Hewson, Alan T.,Hughes, Kevin,Richardson, Steward K.,Sharpe, David A.,Wadsworth, Alan H.
, p. 1565 - 1569 (2007/10/02)
Treatment of o-sulphonamido aryl ketene dithioacetal S-oxides with hydrochloric acid in the presence of hydrogen sulphide gives 2-methylthioindoles.
