109532-22-1

Usage

Uses

Used in Pharmaceutical Synthesis:
Ethanone, 1-(2-amino-3-methylphenyl)-2-chloro(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structural and reactive properties, contributing to the development of new drugs with potential therapeutic benefits.
Used in Research Chemicals:
In the field of research, Ethanone, 1-(2-amino-3-methylphenyl)-2-chloro(9CI) serves as a valuable research chemical, enabling scientists to explore its properties and reactivity in various chemical reactions and processes.
Used in Drug Discovery and Development:
Due to its unique structure, Ethanone, 1-(2-amino-3-methylphenyl)-2-chloro(9CI) is used in drug discovery and development to create novel compounds with potential therapeutic applications. Further research is needed to fully explore its potential uses and properties in this industry.

Upstream product

• 107-14-2 chloroacetonitrile 
• 95-53-4 o-toluidine 

Downstream Products

• 933-67-5 7-methyl-1H-indole 
• 109532-29-8 2-(Acetylamino)-α-chlor-3-methylacetophenon 
• 205995-32-0 2-dimethylaminoacetyl-6-methylaniline 
• 205993-97-1 2-methoxyacetyl-6-methylaniline 
• 1159001-75-8 7-methyl-2-phenyl-1H-indole-3-carbonitrile 
• 59541-82-1 7-methyl-2-phenyl-1H-indole 
• 221697-32-1 2,2-dimethyl-propionic acid 2-dimethylamino-1-[2-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-3-methyl-phenyl]-ethyl ester 
• 221697-31-0 1-(2-amino-3-methyl-phenyl)-2-dimethylamino-ethanol 
• 205995-65-9 (3RS)-1-(3-azabicyclo[3.2.2]nonan-3-yl)carboxymethyl-3-benzyloxycarbonylamino-2,3-dihydro-5-dimethylaminomethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 205994-91-8 (3RS)-1-(3-azabicyclo[3.2.2]nonan-3-yl)carboxymethyl-3-benzyloxycarbonylamino-2,3-dihydro-5-methoxymethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 205995-63-7 (3RS)-3-benzyloxycarbonylamino-2,3-dihydro-5-dimethylaminomethyl-1-ethoxycarbonylmethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 205994-89-4 (3RS)-3-benzyloxycarbonylamino-2,3-dihydro-1-ethoxycarbonylmethyl-5-methoxymethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 205995-64-8 (3RS)-3-benzyloxycarbonylamino-1-carboxymethyl-2,3-dihydro-5-dimethylaminomethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 205994-90-7 (3RS)-3-benzyloxycarbonylamino-1-carboxymethyl-2,3-dihydro-5-methoxymethyl-9-methyl-1H-1,4-benzodiazepin-2-one 

Relevant academic research and scientific papers

Indole-3-carbonitriles as DYRK1A inhibitors by fragment-based drug design

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a potential drug target because of its role in the development of Down syndrome and Alzheimer's disease. The selective DYRK1A inhibitor 10-iodo-11H-indolo[3, 2-c]quinoline-6-carboxy

Dual CCK-A and CCK-B receptor antagonists (II). Preparation and structure activity relationships of 5-alkyl-9-methyl-1,4-benzodiazepines and discovery of FR208419

In our continuing research for dual CCK-A and -B antagonists, according to our hypothesis that dual CCKA and -B antagonists should be more efficacious than selective CCK-A antagonists for the treatment of pancreatitis, we have prepared various 5-alkyl-9-m

Simple Synthesis of Indoles and of Corresponding 3(2H)-Indolone Derivatives, Monosubstituted at the Benzene Ring, as Synthetic Precursors of Natural Compounds

Application of a specific BCl3-catalyzed ortho-chloroacetylation of the monosubstituted primary anilines 2a-e with chloroacetonitrile, as a variant of the Houben-Hoesch reaction, leads to the corresponding 2-amino-α-chloroacetophenones 3a-g.These may be reduced and cyclized to yield the indoles 4a-g or, after acylation to 5a-g and 7a, b converted by base-catalyzed dehydrochlorination into the 1-acyl-3(2H)-indolones 6a-g and 8a, b.