205995-32-0

Upstream product

• 109532-22-1 1-(2-amino-3-methylphenyl)-2-chloroethan-1-one 
• 124-40-3 dimethyl amine 
• 95-53-4 o-toluidine 

Downstream Products

• 221697-32-1 2,2-dimethyl-propionic acid 2-dimethylamino-1-[2-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-3-methyl-phenyl]-ethyl ester 
• 205995-65-9 (3RS)-1-(3-azabicyclo[3.2.2]nonan-3-yl)carboxymethyl-3-benzyloxycarbonylamino-2,3-dihydro-5-dimethylaminomethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 205995-63-7 (3RS)-3-benzyloxycarbonylamino-2,3-dihydro-5-dimethylaminomethyl-1-ethoxycarbonylmethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 205995-64-8 (3RS)-3-benzyloxycarbonylamino-1-carboxymethyl-2,3-dihydro-5-dimethylaminomethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 205995-52-4 (3RS)-3-benzyloxycarbonylamino-2,3-dihydro-5-dimethylaminomethyl-9-methyl-1H-1,4-benzodiazepin-2-one 
• 221697-31-0 1-(2-amino-3-methyl-phenyl)-2-dimethylamino-ethanol 

Relevant academic research and scientific papers

Dual CCK-A and CCK-B receptor antagonists (II). Preparation and structure activity relationships of 5-alkyl-9-methyl-1,4-benzodiazepines and discovery of FR208419

In our continuing research for dual CCK-A and -B antagonists, according to our hypothesis that dual CCKA and -B antagonists should be more efficacious than selective CCK-A antagonists for the treatment of pancreatitis, we have prepared various 5-alkyl-9-m

The intramolecular salt effect in chiral auxiliaries. Enhanced diastereoselectivity in a nitrile oxide cycloaddition via rational transition state stabilization

The use of ion pairs to control a nitrile oxide cycloaddition is demonstrated. A chiral phenylmaleimide derivative bearing an ionic group and an associated counterion provides enhanced selectivity in the cycloaddition of benzonitrile oxide. The intramolecular salt effect controls the orientation of the 1,3-dipolar reagent. The nature of the solvent is shown to be relevant in the selectivity of the reaction.