109541-75-5

Basic information

• Product Name: methyl 1-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)cyclopropanecarboxylate
• Synonyms: methyl 1-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)cyclopropanecarboxylate
• CAS NO: 109541-75-5
• Molecular Formula: C₁₃H₁₁NO₄
• Molecular Weight: 245.23074
• Mol File: 109541-75-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 1-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)cyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)cyclopropanecarboxylate(109541-75-5)
• EPA Substance Registry System: methyl 1-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)cyclopropanecarboxylate(109541-75-5)

Safety Data

• Hazardous Substances Data: 109541-75-5(Hazardous Substances Data)

Upstream product

• 122690-13-5 4-bromo-2-phthalimidobutyric acid methyl ester 
• 85-44-9 phthalic anhydride 
• 5464-44-8 1,3-dihydro-1,3-dioxo-α(CH2CH2SCH3)-2H-isoindole-2-acetate 
• 55985-04-1 methyl (S)-4-methylsulfanyl-2-phthalimidobutanoate 
• 74242-84-5 C₁₃H₁₂ClNO₃S 

Downstream Products

• 68781-13-5 α-amino-cyclopropanecarboxylic acid hydrochloride 
• 22059-21-8 aminocyclopropane-1-carboxylic acid 

Relevant articles and documents

FACILE SYNTHESIS OF D,L-PHOSPHINOTHRICIN FROM METHYL 4-BROMO-2-PHTHALIMIDOBUTYRATE

Synthetic versatility of the title bromide is illustrated by simple preparations of D,L-phosphinothricin, D,L-2-amino-4-phosphonobutyric acid, and aminocyclopropanecarboxylic acid.

4-phosphorus-2-phthalimidobutyrate intermediates

Phosphinylbutanoic acids, such as phosphinothricin, can be prepared by reacting racemic 4-halo-2-phthalimidobutyrates with a tricoordinate phosphorus compound represented by the formula: wherein R1 is methyl or ethyl, and R2 is selected from the group consisting of alkoxy having from one to six carbon atoms, aryloxy, and trialkylsilyloxy groups having from one to twelve carbon atoms, to form an intermediate compound; and hydrolyzing the intermediate compound to form the phosphinylbutanoic acids.