1095945-99-5Relevant articles and documents
Phosphorescent thymidine triphosphate sensor based on a donor-acceptor ensemble system using intermolecular energy transfer
Kwon, Tae-Hyuk,Kim, Hee Jin,Hong, Jong-In
, p. 9613 - 9619 (2008)
An ensemble sensor system that exhibited selective luminescence enhancement upon binding to thymidine 5′-triphosphate (TTP) in HEPES buffer over other nucleotides was developed. The ensemble system consisted of an energy acceptor (Flrpicbis(Zn2+/sup
Molecular recognition and scavenging of arsenate from aqueous solution using dimetallic receptors
Moffat, Chris D.,Weiss, Dominik J.,Shivalingam, Arun,White, Andrew J.P.,Salaun, Pascal,Vilar, Ramon
, p. 17168 - 17177 (2014)
A series of copper(II), nickel(II) and zinc(II) dimetallic complexes were prepared and their affinities towards arsenate investigated. Indicator displacement assays (IDAs) were carried out to establish the complexes with best affinities towards arsenate.
Sticky nanoparticles: A platform for siRNA delivery by a bis(zinc(II) dipicolylamine)-functionalized, self-assembled nanoconjugate
Liu, Gang,Choi, Ki Young,Bhirde, Ashwinkumar,Swierczewska, Magdalena,Yin, Juan,Lee, Sang Wook,Park, Jae Hyung,Hong, Jong In,Xie, Jin,Niu, Gang,Kiesewetter, Dale O.,Lee, Seulki,Chen, Xiaoyuan
, p. 445 - 449 (2012)
Delivering the goods: Multifunctional, self-assembled, polymeric nanoparticles for the simultaneous delivery of small-molecule drugs and siRNA have been synthesized. The nanoparticles are composed of biodegradable hyaluronic acid, for tumor targeting and
Molecular recognition of bisphosphonate-based drugs by di-zinc receptors in aqueous solution and on gold nanoparticles
Chan, Tiffany G.,Torres-Huerta, Aaron,Vilar, Ramon,White, Andrew J. P.
, p. 5939 - 5948 (2020/05/25)
Metal-based anion receptors have several important applications in sensing, separation and transport of negatively charged species. Amongst these receptors, di-zinc(ii) complexes are of particular interest for the recognition of oxoanions, in particular phosphate derivatives. Herein we report the synthesis of a di-zinc(ii) receptor and show that it has high affinity and selectivity for bisphosphonates such as alendronate and etidronate - which are used to treat a number of skeletal disorders as well as showing interesting anticancer properties. The binding mode of the di-zinc(ii) receptor with alendronate and etidronate has been unambiguously established by single crystal X-ray crystallography. In addition, by modifying the backbone of the receptor, we show that the drug-loaded receptor can be attached onto gold nanoparticles as potential drug-delivery vehicles.