109635-50-9Relevant academic research and scientific papers
SYNTHESIS OF 5,11-DIHYDRO-5-OXOPYRIDOPYRIMIDO-BENZIMIDAZOLES AS POTENTIAL ANTITUMOR AGENTS
Caroti, Paola,Ceccotti, Carlo,Settimo, Antonio da,Palla, Fabio,Primofiore, Giampaolo
, p. 263 - 266 (2007/10/02)
The copper-catalyzed reaction between 2-chloropyridine-3-carboxylic acid and 1-alkyl-2-aminobenzimidazoles afforded the 11-alkyl-5,11-dihydro-5-oxopyridopyrimidobenzimidazoles 5b-d which are isosters of 6H-pyridocarbazoles, some of which are used as antitumor agents.The quaternized salts 7 of 5b-d have also been prepared, because they are strictly related to 9-hydroxy-2-methylellipticinium acetate, 6.
