109660-16-4

Upstream product

• 2245-30-9 1,2-epoxy-3,3-dimethylbutane 
• 87100-15-0 cyclohexylboronic acid pinacol ester 
• 108344-92-9 (E)-Me₃CCHCHHgBr 
• 24371-94-6 cyclohexylmercury chloride 
• 917-92-0 3,3-Dimethylbut-1-yne 
• 110-82-7 cyclohexane 
• 917-64-6 methyl magnesium iodide 
• 142039-28-9 2-((E)-2-Cyclohexyl-vinyl)-2-methyl-[1,3]dithiolane 

Relevant academic research and scientific papers

An Improved Method for Stereoselective Synthesis of (E)-Alkenes via Alkenyldialkylboranes

Successive treatments of alkenyldialkylboranes, formed by the reaction of alkynes and sterically hindered dialkylboranes, with alkyllithium and benzenesulfenyl chloride afforded highly pure (E)-alkenes in good or excellent yields.

Iterative synthesis of alkenes by insertion of lithiated epoxides into boronic esters

The insertion of lithiated epoxides into boronic esters followed by thermal syn-elimination provides a stereospecific entry to alkenes. This process avoids transition metals and is amenable to iteration to provide higher substitution patterns.

Stereoselectivity of the Thermally Initiated Free-Radical Chain Addition of Cyclohexane to 1-Alkynes

Alkanes can be added to alkynes in a thermally initiated free-radical chain reaction ("ane reaction").The addition of cyclohexane to 1-alkynes 1a-l yields a mixture of (Z)- and (E)-2-cyclohexyl-1-alkenes 3a-l.An essential step in this reaction is the addi

Electron-transfer processes. 43. Attack of alkyl radicals upon 1-alkenyl and 1-alkynyl derivatives of tin and mercury

Alkyl radicals, obtained by reaction of Bu3Sn? or ClHg? with alkylmercury halides, will undergo regioselective and in some cases stereospecific substitution by a free radical chain addition-elimination mechanism with 1-alkenylstannanes or -mercurials. The chain reaction is also observed for 1-alkynyl derivatives and in the photostimulated demercuration of mixed alkyl and 1-alkenyl- or 1-alkynylmercurials. Chain propagation with alkyl radical formation is also observed to occur in the reactions of β-eliminated ClHg? with Grignard reagents in PhH-THF solution. In competitive reactions of Bu3Sn? or ClHg? with pairs of alkylmercury chlorides, it is observed that a tert-butylmercurial is >1000 times more reactive than a n-butylmercurial, suggesting a concerted dissociate electron-transfer process not involving the intermediacy of RHg? species.