1097-35-4 Usage
Description
4-(Benzyloxy)-N-benzamidoaniline, a chemical compound with the molecular formula C22H19N3O2, is an aniline derivative featuring a benzamide functional group and a benzyloxy group. It is a versatile and valuable chemical compound in the field of medicinal chemistry, known for its potential applications in the development of new drugs and pharmaceutical products, particularly in cancer research.
Uses
Used in Pharmaceutical Research:
4-(Benzyloxy)-N-benzamidoaniline is used as a key intermediate in the synthesis of various pharmaceutical compounds for its versatile reactivity and functional groups. It plays a crucial role in the development of new drugs and pharmaceutical products.
Used in Organic Synthesis:
As a building block in organic synthesis, 4-(Benzyloxy)-N-benzamidoaniline is utilized for the preparation of a wide range of organic compounds, showcasing its reactivity and functional group versatility.
Used in Cancer Research:
4-(Benzyloxy)-N-benzamidoaniline is employed in cancer research for its potential applications in the development of novel anticancer agents. Its biological and pharmacological activities are being studied to explore its potential as a therapeutic agent against various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1097-35-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,9 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1097-35:
(6*1)+(5*0)+(4*9)+(3*7)+(2*3)+(1*5)=74
74 % 10 = 4
So 1097-35-4 is a valid CAS Registry Number.
1097-35-4Relevant articles and documents
Amide bond formation in aqueous solution: Direct coupling of metal carboxylate salts with ammonium salts at room temperature
Nielsen, John,Tung, Truong Thanh
supporting information, p. 10073 - 10080 (2021/12/10)
Herein, we report a green, expeditious, and practically simple protocol for direct coupling of carboxylate salts and ammonium salts under ACN/H2O conditions at room temperature without the addition of tertiary amine bases. The water-soluble coupling reagent EDC·HCl is a key component in the reaction. The reaction runs smoothly with unsubstituted/substituted ammonium salts and provides a clean product without column chromatography. Our reaction tolerates both carboxylate (which are unstable in other forms) and amine salts (which are unstable/volatile when present in free form). We believe that the reported method could be used as an alternative and suitable method at the laboratory and industrial scales. This journal is
Tetrazole NK1 receptor antagonists: The identification of an exceptionally potent orally active antiemetic compound
Armour,Chung,Congreve,Evans,Guntrip,Hubbard,Kay,Middlemiss,Mordaunt,Pegg,Vinader,Ward,Watson
, p. 1015 - 1020 (2007/10/03)
The medicinal chemistry strategy which led to the identification of GR205171, an orally active non-peptide neurokinin-1 receptor antagonist that is the most potent broad-spectrum antiemetic agent reported to date.
