1097193-00-4Relevant academic research and scientific papers
Simple generation of various α-monofluoroalkyl radicals by organic photoredox catalysis: modular synthesis of β-monofluoroketones
Taniguchi, Ryo,Noto, Naoki,Tanaka, Seiya,Takahashi, Keigo,Sarkar, Sujan K.,Oyama, Ryoko,Abe, Manabu,Koike, Takashi,Akita, Munetaka
, p. 2609 - 2612 (2021)
A metal-free and operationally simple strategy for the generation of various α-monofluoroalkyl radicals has been developed. A combination of 1,4-bis(diarylamino)naphthalene photocatalyst and sulfoximine-based fluoroalkylating reagents is the key to succes
list fluoro cyclopropane compound and its preparation method and application
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Paragraph 0189; 0190; 0191; 0192, (2017/02/02)
Disclosed are a monofluoro cyclopropane compound, and preparation method and uses thereof. The structure of the monofluoro cyclopropane compound is as represented by formula I, wherein R1, R2, Ra, and formula II are as defined in the specification. Also p
Br?nsted acid-catalyzed 1,2-fluorine migration with fluoroepoxides
Luo, Tao,Zhang, Rui,Shen, Xiao,Zhang, Wei,Ni, Chuanfa,Hu, Jinbo
supporting information, p. 19636 - 19641 (2015/11/27)
A catalytic 1,2-fluorine migration reaction with simple fluoroepoxides at room temperature is reported. Under Br?nsted acid catalysis, α-fluorinated ketones are efficiently constructed in the absence of an external fluorine source through a 1,2-fluorine migration reaction. The experimental results indicate that the present 1,2-fluorine migration reaction proceeds via a carbocation intermediate.
Efficient synthesis and ring-opening reactions of monofluorinated epoxides derived from α-fluorosulfoximines
Zhang, Wei,Hu, Jinbo
supporting information; experimental part, p. 2799 - 2804 (2010/12/25)
Monofluorinated epoxides were successfully prepared through the O-cyclization reaction between α-fluorosulfoximines and ketones. The obtained fluoroepoxides were found to readily undergo an interesting ring-opening process (involving both a C-F bond cleavage and another C-F bond formation) in the presence of titanium tetrafluoride or pyridinium poly(hydrogen fluoride) to afford α-fluorinated ketones. The later process constitutes a formal catalytic 1,2-fluorine shift reaction.
