1097196-96-7

Usage

Uses

Used in Research Applications:
(1R)-1-[4-(methoxycarbonyl)phenyl]ethanaminium chloride is used as a research tool for studying mitochondrial function and its role in cell death. Its ability to inhibit adenine nucleotide translocase makes it a valuable compound for understanding the mechanisms of oxidative phosphorylation and ATP synthesis.
Used in Therapeutic Applications:
(1R)-1-[4-(methoxycarbonyl)phenyl]ethanaminium chloride is being studied for its potential as a therapeutic agent for diseases involving mitochondrial dysfunction. Its ability to disrupt mitochondrial function and induce cell death may have implications for the treatment of certain conditions, although its toxic nature must be carefully considered and managed.

Upstream product

• 67-56-1 methanol 
• 1134776-30-9 (R)-4-(1-tert-butoxycarbonylaminoethyl)benzoic acid 
• 1134776-39-8 (R)-4-(1-aminoethyl)benzoic acid hydrochloride 

Downstream Products

• 1207861-08-2 methyl 4-[(1R)-1-({[2,5-dichloro-4-(3-chlorobenzyl)-3-thienyl]carbonyl}amino)ethyl]benzoate 
• 1242847-74-0 N-[(1R)-1-[4-[(tert-butylamino)methyl]phenyl]ethyl]-2-[2-(p-tolylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl]acetamide 
• 1242850-78-7 (R)-4-(1-(tert-butoxycarbonylamino)ethyl)benzyl methanesulfonate 
• 1242850-79-8 (R)-tert-butyl 1-(4-((tert-butylamino)methyl)phenyl)ethylcarbamate 
• 1242850-57-2 (R)-N-(4-(1-aminoethyl)benzyl)-2-methylpropan-2-amine 
• 1021491-26-8 tert-butyl N-[(1R)-1-[4-(hydroxymethyl)phenyl]ethyl]carbamate 
• 1220902-93-1 C₂₃H₂₆Cl₂N₂O₅ 
• 1220902-94-2 C₁₈H₁₈Cl₂N₂O₃ 
• 1220904-44-8 C₃₁H₃₇Cl₂N₃O₅ 
• 1220904-45-9 C₃₁H₃₇Cl₂N₃O₅ 
• 1220902-60-2 C₂₈H₃₁Cl₂N₇O₂ 
• 1220903-06-9 C₂₇H₂₉Cl₃N₂O₂ 
• 1220897-33-5 C₃₀H₃₅Cl₂N₃O₅ 
• 1220904-36-8 C₂₇H₃₂Cl₂N₂O₄ 

Relevant academic research and scientific papers

Functionalized Chiral Bambusurils: Synthesis and Host-Guest Interactions with Chiral Carboxylates

Bambusurils are a class of macrocyclic anion receptors that exhibit notable anion recognition properties, able to bind various inorganic anions as well the carboxylates or sulfonates. Recently, we reported enantioselective recognition of chiral carboxylates using non-functionalized chiral bambusuril derivatives. Herein, we report the synthesis and host-guest properties of two new representatives of chiral bambusuril macrocycles bearing ester functional groups, differing by the substituents attached to their portals. Their supramolecular properties in terms of carboxylate binding were studied by means of NMR in DMSO-d6. The reported bambusurils bind selected chiral carboxylates with enantioselectivity factors up to 3.1. The results indicated that the selectivity towards different carboxylates is governed by the steric constraint of the substituents surrounding bambusuril portals. No clear trend in the binding affinities and their enantioselectivities was found.

AMIDE COMPOUND

[Problems] To provide a compound that is useful as an agent for treating chronic renal insufficiency or an agent for treating diabetic nephropathy. [Means for Solving Problems] The present inventors have conducted extensive studies on a compound having an

SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS

Disclosed are compounds of formula (I) which are bradykinin B1 receptor (B1R) antagonists. These compounds are useful to treat diseases or relieve adverse symptoms associated with inflammation and pain. The invention encompasses novel compounds and acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases involving inflammation and pain.

THIOPHENECARBOXAMIDE DERIVATIVES AS EP4 RECEPTOR LIGANDS

The invention is directed to thiophenecarboxamide derivatives of formulae I and II as EP4 receptor ligands, antagonists or agonists, useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoi