1097221-10-7

Upstream product

• 1097221-34-5 (4-chlorophenyl)[2-(phenylamino)pyridin-3-yl]methanone 
• 84199-53-1 bromo-2 lithio-3 pyridine 
• 14062-80-7 N,N-dimethyl-4-chlorobenzamide 
• 1679-18-1 4-Chlorophenylboronic acid 
• 271-63-6 7-Azaindole 
• 591-50-4 iodobenzene 
• 74420-15-8 3-bromo-1H-pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

Ruthenium-Catalyzed Direct and Selective C-H Cyanation of N-(Hetero)aryl-7-azaindoles

An efficient, highly regioselective, and scalable ruthenium-catalyzed o-aryl C-H mono-cyanation of N-aryl-7-azaindoles to form N-(2-cyanoaryl)-7-azaindoles has been developed through N-directed ortho C-H activation using N-cyano-N-phenyl-p-toluenesulfonam

Rhodium-catalyzed regioselective C-H chlorination of 7-azaindoles using 1,2-dichloroethane

An unexpected rhodium-catalyzed regioselective C-H chlorination of 7-azaindoles was developed using 1,2-dichloroethane (DCE) as a chlorinating agent and 7-azaindole as the directing group. This protocol provides an efficient access to ortho-chlorinated azaindoles with operational simplicity, good functional group tolerance, and a wide substrate scope. (Chemical Equation Presented).

Synthesis of 1-aryl-1H-pyrrolo[2,3-b]pyridines (1-aryl-7-azaindoles) by a thermal dehydration-cyclization-dehydrogenation sequence of 2-arylamino-3-(1- hydroxyalkyl)pyridines

1-Aryl-1H-pyrrolo[2,3-b]pyridines (1-aryl-7-azaindoles) have been prepared in reasonable yields from the corresponding 2-arylamino-3-(1-hydroxyalkyl) pyridines, on heating at ca. 250 °C, through a successive dehydration/cyclization/dehydrogenation sequenc