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1-(4-Fluorophenyl)-2-phenylquinazolin-4(1H)-one, also known as FQPQ, is a quinazolinone derivative with a molecular formula of C21H13FN2O. It is a crystalline white powder with a melting point of 274-276°C. FQPQ has been studied for its potential pharmaceutical applications, particularly as an antitumor agent. It has been shown to inhibit the growth of various cancer cells, including lung and breast cancer, by inducing apoptosis and disrupting cell cycle progression. Additionally, FQPQ has shown anti-inflammatory and antioxidant properties, making it a promising candidate for further research and development in the field of medicine.

1098-24-4

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1098-24-4 Usage

Uses

Used in Pharmaceutical Industry:
1-(4-Fluorophenyl)-2-phenylquinazolin-4(1H)-one is used as an antitumor agent for its ability to inhibit the growth of various cancer cells, such as lung and breast cancer, by inducing apoptosis and disrupting cell cycle progression.
Used in Anti-inflammatory Applications:
1-(4-Fluorophenyl)-2-phenylquinazolin-4(1H)-one is used as an anti-inflammatory agent due to its demonstrated anti-inflammatory properties, which can be beneficial in the treatment of various inflammatory conditions.
Used in Antioxidant Applications:
1-(4-Fluorophenyl)-2-phenylquinazolin-4(1H)-one is used as an antioxidant agent for its potential to protect cells from oxidative stress and damage, which can contribute to the development of various diseases and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1098-24-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,9 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1098-24:
(6*1)+(5*0)+(4*9)+(3*8)+(2*2)+(1*4)=74
74 % 10 = 4
So 1098-24-4 is a valid CAS Registry Number.

1098-24-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-fluoro-phenyl)-2-phenyl-1H-quinazolin-4-one

1.2 Other means of identification

Product number -
Other names 1-(4-Fluorphenyl)-3,4-dihydro-2-phenyl-4-chinazolinon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1098-24-4 SDS

1098-24-4Downstream Products

1098-24-4Relevant academic research and scientific papers

Synthesis of quinazolin-4(1 H)-ones via amination and annulation of amidines and benzamides

Hu, Fangpeng,Cui, Xinfeng,Ban, Zihui,Lu, Guoqiang,Luo, Nan,Huang, Guosheng

, p. 2356 - 2360 (2019/03/06)

Quinazolinones have broad applications in the biological, pharmaceutical and material fields. Studies on the synthesis of these compounds are therefore widely conducted. Herein, a novel and highly efficient copper-mediated tandem C(sp2)-H amination and annulation of benzamides and amidines for the synthesis of quinazolin-4(1H)-ones is proposed. This synthetic route can be useful for the construction of quinazolin-4(1H)-one frameworks.

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