109810-35-7

Basic information

• Product Name: phenyl(pyridin-2-yl)(p-tolyl)methanol
• Synonyms: phenyl(pyridin-2-yl)(p-tolyl)methanol
• CAS NO: 109810-35-7
• Molecular Weight: 275.35
• Mol File: 109810-35-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: phenyl(pyridin-2-yl)(p-tolyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl(pyridin-2-yl)(p-tolyl)methanol(109810-35-7)
• EPA Substance Registry System: phenyl(pyridin-2-yl)(p-tolyl)methanol(109810-35-7)

Safety Data

• Hazardous Substances Data: 109810-35-7(Hazardous Substances Data)

Upstream product

• 499-83-2 Pyridine-2,6-dicarboxylic acid 
• 134-84-9 4-Methylbenzophenone 
• 1121-60-4 pyridine-2-carbaldehyde 
• 106-38-7 para-bromotoluene 
• 29263-67-0 α-(4-methylphenyl)-2-pyridinemethanol 
• 91-02-1 phenyl(pyridin-2-yl)methanone 

Relevant articles and documents

Green synthesis method of polyaryl substituted methanol

The invention relates to a green synthesis method of polyaryl substituted methanol, in particular to a method for efficiently synthesizing polyaryl substituted methanol in a polar aprotic solvent under the condition of an oxidizing agent by taking polyaryl substituted methane as a raw material and alkali as an additive. The method provided by the invention is green and environment-friendly, avoids using expensive metal catalysts, and has the advantages of low cost, few reaction steps, short time, high yield and the like.

Iron-catalyzed C-H bond functionalization for the exclusive synthesis of pyrido[1,2-a]indoles or triarylmethanols

The efficient and selective iron-catalyzed C-H activation of 2-benzhydrylpyridine derivatives was employed for the preparation of pyrido[1,2-a]indoles through an intramolecular C-H amination reaction. In the presence of molecular oxygen as the sole oxidant, the same 2-benzhydrylpyridines were also used for the synthesis of the corresponding tertiary alcohols. In these approaches, the iron catalyst was used to selectively activate the C(sp2)-H bond of 2-benzhydrylpyridine, in the case of the intramolecular ring-closing C-H amination reaction in which the pyridine nitrogen atom was a directing group as well as a nucleophile, and the C(sp3)-H bond of the same compound, in the case of the oxidation reaction to give the corresponding triaryl carbinol.