1098215-41-8

Basic information

• Product Name: ethyl 2-({2-[benzy(trifluoroacetyl)amino]-3,3,3-trifluoro-2-methylpropanoyl}amino)propanoate
• CAS NO: 1098215-41-8
• Molecular Weight: 442.358
• Mol File: 1098215-41-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-({2-[benzy(trifluoroacetyl)amino]-3,3,3-trifluoro-2-methylpropanoyl}amino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-({2-[benzy(trifluoroacetyl)amino]-3,3,3-trifluoro-2-methylpropanoyl}amino)propanoate(1098215-41-8)
• EPA Substance Registry System: ethyl 2-({2-[benzy(trifluoroacetyl)amino]-3,3,3-trifluoro-2-methylpropanoyl}amino)propanoate(1098215-41-8)

Safety Data

• Hazardous Substances Data: 1098215-41-8(Hazardous Substances Data)

Upstream product

• 33140-27-1 ethyl 2-isocyanopropionate 
• 119561-23-8 N-1,1,1-trifluoropropan-2-ylidene-1-phenylmethanamine 
• 76-05-1 trifluoroacetic acid 

Relevant articles and documents

The Ugi reaction with CF3-carbonyl compounds: effective synthesis of α-trifluoromethyl amino acid derivatives

The Ugi reaction with CF3-carbonyl compounds is described in detail. The method is efficient for the multicomponent preparation of α-trifluoromethyl (Tfm) amino acids, α-Tfm containing dipeptides, and iminodicarboxylic acids. In addition, the first protected CF3-opine derivative was prepared. The scope, limitations, and stereochemistry of the approach are discussed.