1098374-65-2

Upstream product

• 55661-08-0 4-methoxy-2,6-dimethylbenzenesulfonyl chloride 
• 74-89-5 methylamine 

Downstream Products

• 1211571-22-0 ethyl 5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-2-carboxylate 
• 1211571-81-1 ethyl 5-(1-{[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}ethyl)furan-3-carboxylate 

Relevant academic research and scientific papers

NEW BRADYKININ B1 ANTAGONISTS

The invention relates to compounds of formula (I) where in R1, R1a, R1b, R2, R3 and X, X1, X2, X3 have the meaning as cited in the description and the claims. Said compounds are useful as Bradykinin B1 antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.

Novel arylsulphonamide derivatives and use thereof as therapeutic agents

The present invention relates to novel arylsulphonamide compounds, defined by formula I and the description, as well as their method of preparation and their therapeutic use.